Comparative phytochemical study of methanolic and ethanolic extracts of <i>Thymus linearis</i> and their antibacterial and antioxidant potential

Nadeem, Hafiz Amir; Pervaiz, Muhammad; Ejaz, Anam; Saeed, Zohaib; Imran, Muhammad; Khan, Rana Rashad Mahmood; Younas, Umer

doi:10.1002/bmc.5808

Cited by 1 publication

(1 citation statement)

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“…Thyme (Thymus vulgaris L.) is a widely used aromatic plant in traditional medicine to treat various diseases including diarrhea, fever, cough, irritation, skin diseases, rheumatism, respiratory disorders, influenza, and digestive problems. It contains various classes of secondary metabolites such as terpenoids, alkaloids, flavonoids, tannins, coumarins, quinones, carotenoids, and steroids with potent antibacterial, antifungal, antipyretic, antinociceptive, antioxidant, and anti-inflammatory effects [104][105][106]. It has a proven antitussive effect with double-blind studies in children and adults, especially combined with ivy extract [107,108].…”

Section: Other Herbal Medicinesmentioning

confidence: 99%

Well-Established and Traditional Use of Vegetal Extracts as an Approach to the “Deep Roots” of Cough

Pecoraro,

Peterle,

Dalla Benetta

et al. 2024

Children

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Cough is a common presenting symptom for patients in a primary care setting and significantly impacts a patient’s quality of life. Cough involves a complex reflex arc beginning with the stimulation of sensory nerves that function as cough receptors that stimulate the cough center in the brain. This “cough center” functions to receive these impulses and produce a cough by activating efferent nervous pathways to the diaphragm and laryngeal, thoracic, and abdominal musculature. Drugs that suppress the neural activity of cough are non-specific as those treatments are not directed toward pathogenic causes such as inflammation and oxidative stress. Moreover, they block a reflex called the watchdog of the lung and have a defense mechanism. Acute respiratory infections of the upper and lower airways most commonly cause acute cough. In contrast, the most common causes of chronic cough are upper airway cough syndrome, asthma, and gastroesophageal reflux disease, all associated with an inflammatory reaction at the level of the cough receptors. The use of natural compounds or herbal drugs such as carob syrup, dry blackcurrant extract, dry extract of caraway fruit, dry extract of ginger rhizome, dry extract of marshmallow root, and dry extract of ivy leaves, to name a few, not only have anti-inflammatory and antioxidant activity, but also act as antimicrobials, bronchial muscle relaxants, and increase gastric motility and empty. For these reasons, these natural substances are widely used to control cough at its deep roots (i.e., contrasting its causes and not inhibiting the arch reflex). With this approach, the lung watchdog is not put to sleep, as with peripheral or central inhibition of the cough reflex, and by contrasting the causes, we may control cough that viruses use at self-advantage to increase transmission.

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Section: Other Herbal Medicinesmentioning

confidence: 99%