Comparative phytochemical evaluation, antimicrobial and antioxidant properties of Pleurotus ostreatus

Abstract

This study scientifically examined the phytochemistry, antioxidant and antimicrobial potencies of two organic extracts of Pleurotus ostreatus. Generally, both extracts were effective against 89.8% of the isolates tested with Bacillus subtilis (7.6 -7.8 mm), Escherichia coli (7.6 -8.2 mm) and Saccharomycee cerevisae (10.5 -10.8 mm) exhibiting highest gram ±ve, gram -ve and fungal susceptibilities by agar well diffusion method, respectively. However, petroleum ether extract (PE) exhibited greater anti-gram negative bacterial activity than the acetone extract (AE) and further produced growth inhibition of these isolates in broth. Compared to PE, the acetone extract elicited higher total phenolic content and in vitro antioxidant capacity. Phytochemical analyses of the extracts revealed low to moderate levels of terpenoids, tannins, steroidal glycosides and carbohydrates, while flavonoids, alkaloids and cynogenic glycosides were not detected. The results indicate that P. ostreatus possesses antimicrobial and antioxidant potentials.

Total Phenolic Content, Antioxidant and Antimicrobial Properties of Pleurotus ostreatus Grown on Lime (Tilia Tomentesa) Leaves

“…Compared to other studies, P. ostreatus was able to inhibit E.coli, B. cerreus, Listeria innocua [47] and other gram positive or negative bacteria and fungi isolates [48]. Other mushrooms such as Morchella conica [49], Ramaria flava [50], Lycoperdon pusilum ve L. Giganteum [51] have also been reported to have antimicrobial activity against many microbes.…”

Between the Bioactive Extracts of Edible Mushrooms and Pharmacologically Important Nanoparticles: Need for the Investigation of a Synergistic Combination - A Mini Review

“…The radical scavenging property of L. deliciosus has also been reported to be higher than the activity of most conventional antioxidants such as butylated hydroxytoluene and trolox [12]. Early research has shown that isolates from mushrooms have anticancer, cardiovascular, antiviral, antiparasitic, antibacterial, anti-inflammatory, blood lipid-lowering, immune response stimulating, and even antidiabetic effects [34][35][36]. Currently, extracts from several mushrooms including L. deliciosus have widespread application in Japan, Korea, and China, being used as potential adjuvants to radiation and chemotherapy [10,13].…”

“…The two most recognized immune systems are the innate and the adaptive immune systems, both working in a specialized and functionalized pattern to ward off infection [34]. Evidence of a cross-link between the specialized cells of the two immune systems exists, such as the neutrophils which are innate cells but also involved in the workings of the adaptive immune system [35]. Farrera and Fadeel had proposed, during the study of the relationship between the immune system and engineered nanomaterials, that most, if not all, of the adverse effects of engineered nanomaterials are exerted through direct effects on the cells of the innate system.…”

Oyster Mushroom : Answer to Human Ailments:a Review

“…Pleurotus species have been found to combat simple and multiple drugresistant isolates of Escherichia coli, Staphylococcus epidermidis, and Staphylococcus aureus [28] and species of Candida [29], Streptococcus, and Enterococcus [30][31][32][33]. Methanolic extracts of Pleurotus species demonstrated an inhibition in growth of Bacillus megaterium, S. aureus, E. coli, Klebsiella pneumoniae, Candida albicans, Candida glabrata, species of Trichophyton and Epidermophyton to different degrees that were lower with respect to two antifungal agents: Streptomycin and nystatin [28].…”