Comparative pharmacognostic studies of three Phyllanthus species

Chemical constituents and antimicrobial properties of <i>Phyllanthus amarus</i> (Schum & Thonn)

“…Literature indicated the application of the plant in the treatment and management of kidney problems, appendix inflammation, prostate problems, pain, gonorrhea, diabetes and chronic dysentery. Topically, it is used for several skin-related problems ranging from skin ulcers, sores, swelling, itchiness, wounds, bruises, scabies, ulcers, sores, edematous swellings, tubercular ulcers, ringworm, scabby and crusty lesions (Khartoon et al,2004;Sen and Batra, 2013;Ushie et al, 2013). Other reported pharmacological activities of the plant include anticancer, antioxidant, antileptospiral, antimicrobial, anti-diabetic, antiinflammatory and anti-convulsant activities (Rajeshkumar et al, 2002;Lim and Murtijaya, 2007;Chandan et al, 2012;Oluwafemi and Debiri, 2008;Bahar, 2011;Evi and Degbeku, 2011;Saranraj and Sivasakthivelan, 2012;Adeolu and Sunday, 2013;Manikkoh et al, 2011;Uander et al,1995).…”

Preliminary Phytochemical Analysis of Solanum nigrum L. Variant Black and Orange Fruited

“…Extractive value profiles help in the detection of adulterants during the process of authentication of crude and raw drug materials. Earlier works had revealed extractive value profiles in several medicinal plants (Sharma and Habib, 1995;Khatoon et al, 2006).…”

The Use of Brazilian Medicinal Plants to Combat Schistosoma mansoni

“…Although many of its compounds are chemically known, the properties of most of these compounds remain unknown. Some pharmacological activities of P. amarus have already been confirmed by scientific studies, such as: (1) treatment for hepatitis B, by suppression of the replication of the virus (Thyagarajan et al, 1988), (2) hepatoprotective effect against actions of paracetamol, carbon tetrachloride (CCl4), galactosamine and alcohol (Krithika et al, 2009, Pramyothin et al, 2007) -phyllanthin and hypophyllanthin, which are lignans present in P. amarus, are described as having hepatocyte-protective action against carbon tetrachloride (Khatoon et al, 2006), (3) aqueous extracts from P. amarus have shown a strong inhibitory action against hepatic carcinoma (Rajeshkumar & Kuttan, 2000), (4) possible antispasmodic effects of the extract on the smooth musculature have been reported because they contribute to the effects on the renal calculi (Kassuya et al, 2003), (5) antibacterial activity of the ethanolic extract (Kloucek et al, 2005), (6) potential anti-inflammatory activity of both the hexane extract and the chemical fraction rich in lignans, obtained from the leaves of P. amarus. The anti-inflammatory activity of lignans was evaluated and it was noticed that nirantin is the most active substance of this fraction.…”

“…In Brazil, plants of the genus Phyllanthus are popularly known as stone-breaker (quebrapedra, arrebenta-pedra or erva-pombinha in Brazilian Portuguese) and are recognised in folk medicine in Brazil and other countries for their diuretic properties. They are used in the treatment for kidney and bladder disorders, helping in the passage of renal calculi, and also act on intestinal infections, diabetes and hepatitis B (Calixto et al, 1998, Jain et al, 2003, Khatoon et al, 2006, Rajakannan et al, 2003, Torres et al, 2003. A large variety of species of plants belonging to this genus have been phytochemically and pharmacologically investigated and many molecules have been isolated and identified.…”