Comparative morphology of the gallbladder and biliary tract in vertebrates: Variation in structure, homology in function and gallstones

Oldham-Ott, Carla K.; Gilloteaux, Jacques

doi:10.1002/(sici)1097-0029(19970915)38:6<571::aid-jemt3>3.0.co;2-i

Cited by 49 publications

(39 citation statements)

References 139 publications

(153 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This gallbladder histological architecture corresponds well to the classic pattern as described in most vertebrates (Oldham-Ott and Gilloteaux, 1997). However, the peculiar cellular morphology and content of the gallbladder mucosal epithelial cells probably correspond with the physiology and niche habits of this species of perciform.…”

Section: Discussionsupporting

confidence: 84%

“…The fibromuscular layer, 200-300 lm thick, has longitudinal, oblique, and cross-sections of smooth muscle bundles, similar to many vertebrate gallbladders (Oldham-Ott and Gilloteaux, 1997). An unusual finding is the presence of a structure, possibly fibroblasts or macrophages laden with lipid enriched by cholesterol, in the same micrographic views as those collected by Roth et al (1988) in the cornea of patients afflicted by lipid keratopathy and in macrophages of atherosclerosis (Stary, 2000).…”

Section: Discussionmentioning

confidence: 90%

“…Having studied and surveyed the same organ in omnivorous types of fish and other vertebrates (Gilloteaux et al, 1995;Gilloteaux, 1997;Oldham-Ott and Gilloteaux, 1997), we were curious as to how this gallbladder would be organized morphologically, considering this species with its exclusively carnivorous and predatory habits. This gallbladder histological architecture corresponds well to the classic pattern as described in most vertebrates (Oldham-Ott and Gilloteaux, 1997).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The Gallbladder ofUranoscopus ScaberL. (Teleost Perciform Fish) is Lined by Specialized Cholecystocytes

Gilloteaux

Ott

Oldham-Ott

2011

The Anatomical Record

Self Cite

View full text Add to dashboard Cite

The gallbladder of Uranoscopus exhibits a mucosal surface layer of simple columnar epithelium composed of specialized cholecystocytes. The apices show storage and mucous secretions, typical microvilli, and very apical projections extending deep into the luminal contents. Many organelles and heterogeneous vesicles of diverse size fill the cytoplasm, including neutral mucins, mitochondria, peroxisomes, lysosomal bodies, and lipid-rich deposits with cholesterol inclusions. The fibromuscular layer shows little blood supply and contains scattered lymph-like walls with minute cholesterol inclusions. The remaining muscular, subserosal, and serosal or adventitial layers of this species do not show any histologic differences to those of other Vertebrates. It was unexpected to find cholesterol inclusions in the fatty deposits of the cholecystocytes, similar to those noted in human cholesterolosis and in some forms of hypercholesterolemia, in this teleostean. In addition, aggregations of mitochondria and anomalous mitochondrial morphologies were found that resemble oncocytoma-like changes. Anat Rec, 294:1890Rec, 294: -1903Rec, 294: , 2011. V V C 2011 WileyLiss, Inc.

show abstract

Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Gallbladder ofUranoscopus ScaberL. (Teleost Perciform Fish) is Lined by Specialized Cholecystocytes

Gilloteaux

Ott

Oldham-Ott

2011

The Anatomical Record

Self Cite

View full text Add to dashboard Cite

show abstract

“…Why a gallbladder is present in most animals but absent in others is still under discussion (Gilloteaux 1997;Oldham-Ott & Gilloteaux 1997).…”

Section: Introductionmentioning

confidence: 99%

The microvasculature of the gallbladder in adultXenopus laevis(Amphibia, Anura): A scanning electron microscope study of vascular corrosion casts and correlative light microscopy

Lametschwandtner

Bartel

Minnich

et al. 2011

Italian Journal of Zoology

View full text Add to dashboard Cite

Microvasculature, anatomy and histomorphology of the gallbladder of the adult pipid frog, Xenopus laevis (Daudin) were studied by light (LM) and scanning electron microscopy (SEM) of tissue preparations and vascular corrosion casts. The thin wall of the gallbladder consisted of columnar epithelium, lamina propria, a fibromuscular layer, subserosa and serosa. A few diverticula but no epithelial folds were present. Up to five cystic arteries arose from the adjacent right hepatic artery and approached the gallbladder via its neck region. One to two cystic veins departed from the bottom and drained into the nearby abdominal vein. Cystic arteries were of the pinnate-type and embraced the gallbladder with their branches. Terminal arterioles gave rise to wide subepithelial capillaries. Transition distances from arteries to veins were short. In general, three to four layers of blood vessels built the vascular bed of the gallbladder wall. The wide subepithelial capillaries established an interface well adapted (1) to allow capillary circulation over a wide range of filling states of the gallbladder and (2) to serve the exchange processes taking place between stored bile and the blood vascular system via the microvillous columnar epithelium.

show abstract

“…In previous studies the ultrastructure of the normal mucosa, ultrastructural observations regarding mucoid material and lipids have been outlined [2,3,4,5,6]. It was early evident that alterations in the cholecystocytes were only identified with ultrastructural examinations.…”

mentioning

confidence: 99%

Chronic Cholecystitis

Nesland

2004

Ultrastructural Pathology

View full text Add to dashboard Cite

Comparative morphology of the gallbladder and biliary tract in vertebrates: Variation in structure, homology in function and gallstones

Cited by 49 publications

References 139 publications

The Gallbladder ofUranoscopus ScaberL. (Teleost Perciform Fish) is Lined by Specialized Cholecystocytes

The Gallbladder ofUranoscopus ScaberL. (Teleost Perciform Fish) is Lined by Specialized Cholecystocytes

The microvasculature of the gallbladder in adultXenopus laevis(Amphibia, Anura): A scanning electron microscope study of vascular corrosion casts and correlative light microscopy

Chronic Cholecystitis

Contact Info

Product

Resources

About