XIth International Congress on Thrombosis and Haemostasis 1987
DOI: 10.1055/s-0038-1644166
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Comparative Investigation of Clotting and Chromogenic Assays for Heparin and Low Molecular Weight Heparin-(Oid) in Plasma of Volunteers and Patients

Abstract: Two recently developed and simplified anti-Xa methods, a chromogenic assay and a clot-based assay (Heptest) were investigated on their accuracy and ex-vivo characteristics. The coefficients of variation (c.v.) for heparin, a heparin fragment (K 2165) and a LMW hepa-rinoid (Org 10172) were respectively: Heptest, within assay c.v.: 5.4; 4.5; 5.0 % between-assay c.v.: 7.8; 5.8; 9.5 %. Chromogenic Anti-Xa assay, within assay c.v.: 3.7; 5.6; 4.6 %, between assay c.v.: 6.6; 8.2; 12.1 %. In plasma samples obtained fr… Show more

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