Comparative investigation of aerial part and root in Lamiophlomis rotata using UPLC-Q-Orbitrap-MS coupled with chemometrics

Li, Tong; Li, Jia; Du, Ruijiao; Liu, Chengjuan; Huang, Shengjie; Yu, Heshui; Han, Lifeng; Chen, Xiaopeng; Wang, Yuefei; Jiang, Miaomiao

doi:10.1016/j.arabjc.2022.103740

Cited by 2 publications

(2 citation statements)

References 38 publications

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“…Fifty-eight components from L. rotata were identified using a combination of standard comparison and literature comparison approaches, including flavonoids, iridoid glycosides, and phenylethanoids. 17 Fig. 1 depicts the UPLC-HRMS profiles of L. rotata , and Table 1 lists the 58 chemical components identified by mass spectrometry.…”

Section: Resultsmentioning

confidence: 99%

“…The anti-inflammatory active ingredients (apigenin, luteolin, caffeic acid, 2 00 -acetylastragalin, astragalin 6-gallate and hyperoside) were screened by network pharmacology in our prior study. 17 Therefore, these 6 active components were employed as small molecule ligands to dock with each of the aforementioned 3 proteins. Results revealed that the 6 compounds had strong binding affinity for the 3 receptor proteins and low conformational energy (Fig.…”

Section: Serum Lipid Profiling By Q-exactive-orbitrap Msmentioning

confidence: 99%

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Lamiophlomis rotata attenuates rheumatoid arthritis by regulating sphingolipid and steroid hormone metabolism

Zhou

et al. 2023

Mol. Omics

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Section: Resultsmentioning

confidence: 99%

Section: Serum Lipid Profiling By Q-exactive-orbitrap Msmentioning

confidence: 99%

Lamiophlomis rotata attenuates rheumatoid arthritis by regulating sphingolipid and steroid hormone metabolism

Zhou

et al. 2023

Mol. Omics

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Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

et al. 2022

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In this review paper, the occurrence in the plant kingdom, the chemophenetic value and the biological activities associated with two specific phenyl-ethanoid glycosides, i.e., leucosceptoside A and leucosceptoside B, were reported. This is the first work ever conducted on such a subject. Analysis of the literature data clearly led to three important conclusions: leucosceptoside A is much more common in plants than leucosceptoside B; leucosceptoside A exerts more biological activities than leucosceptoside B even if nothing can be generally concluded about which one is actually the most potent; neither of these compounds can be used as a chemophenetic marker. These three aspects and more are discussed in more depth in this work.

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Comparative investigation of aerial part and root in Lamiophlomis rotata using UPLC-Q-Orbitrap-MS coupled with chemometrics

Cited by 2 publications

References 38 publications

Lamiophlomis rotata attenuates rheumatoid arthritis by regulating sphingolipid and steroid hormone metabolism

Lamiophlomis rotata attenuates rheumatoid arthritis by regulating sphingolipid and steroid hormone metabolism

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

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