Comparative immunomodulatory effects in mice and in human dendritic cells of five bacterial strains selected for biocontrol of leafy green vegetables

Uhlig, Elisabeth; Elli, Giulia; Nurminen, Noora; Oscarsson, Elin; Canaviri-Paz, Pamela; Burri, Stina; Rohrstock, Anne-Marie; Rahman, Milladur; Alsanius, Beatrix; Molin, Göran; Zeller, Kathrin S.; Håkansson, Åsa

doi:10.1016/j.fct.2022.113064

Cited by 2 publications

(2 citation statements)

References 33 publications

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“…The United Nations General Assembly has declared 2021 as the "International Year of Fruits and Vegetables" to draw attention to its importance in human health and nutrition (Food and Agriculture Organization [FAO], 2021). Regular consumption of fresh green leafy vegetables (FGLVs) is reported to reduce the risk of stroke, hypertension, cardiovascular, and other chronic diseases eventually increasing life expectancy and quality (Lee et al, 2022;Uhlig et al, 2022). FGLVs contain high levels of carotenoids, hepatitis A virus from irrigation water, operating environment, and/or handling personnel (Bosch et al, 2018;Callejón et al, 2015;Ferrario et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Cold plasma application to fresh green leafy vegetables: Impact on microbiology and product quality

Özdemir,

Başaran,

Kartal

et al. 2023

Comp Rev Food Sci Food Safe

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Fresh green leafy vegetables (FGLVs) are consumed either garden‐fresh or by going through very few simple processing steps. For this reason, foodborne diseases that come with the consumption of fresh products in many countries have prioritized the development of new and reliable technologies to reduce food‐related epidemics. Cold plasma (CP) is considered one of the sustainable and green processing approaches that inactivate target microorganisms without causing a significant temperature increase during processing. This review presents an overview of recent developments regarding the commercialization potential of CP‐treated FGLVs, focusing on specific areas such as microbial inactivation and the influence of CP on product quality. The effect of CP differs according to the power of the plasma, frequency, gas flow rate, application time, ionizing gases composition, the distance between the electrodes and pressure, as well as the characteristics of the product. As well as microbial decontamination, CP offers significant potential for increasing the shelf life of perishable and short‐shelf‐life products. In addition, organizations actively involved in CP research and development and patent applications (2016–2022) have also been analyzed.

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Section: Introductionmentioning

confidence: 99%

Cold plasma application to fresh green leafy vegetables: Impact on microbiology and product quality

Özdemir,

Başaran,

Kartal

et al. 2023

Comp Rev Food Sci Food Safe

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“…Moreover, foodborne diseases are widely caused by Enterobacteriaceae, which is highly spread among various aquatic systems to be colonized in humans, causing urinary tract infections. In addition, the abuse of antibiotics in the aquatic environment has led to the emergence of new bacterial Enterobacter strains [35][36][37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Bacterial Co-Infection as a Potential Threat to Farmed Flathead Grey Mullet (Mugil cephalus): Phenotypic and Molecular Diagnosis, Histopathology, Immunity Response, and In Vitro Antibacterial Evaluation

Elbahnaswy

Elshopakey

Shakweer

et al. 2023

Fishes

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Vibrio alginolyticus, Vibrio chlorea, and Enterococcus cloacae were the main bacterial pathogens investigated during recurrent episodes of mortalities among farmed flathead grey mullet (Mugil cephalus) in the Bahar El-Baqar area, Sharqia governorate, Egypt, during the summer season in 2021. Nevertheless, the contamination of water with heavy metals was evaluated. In this study, a total number of sixty moribund and freshly dead Mugil cephalus were examined clinically and upon post-mortem. Then, the bacterial isolates were subjected to bacteriological phenotypic examination, 16S rRNA gene sequencing, and antibiotic sensitivity testing. Histopathological screening and the immunity response of naturally infected M. cephalus were also implemented. In areas where bacterial strains were recovered in a high percentage, water contamination with Cu, Fe, and Ni was higher than the permissible limit. The results showed a high similarity (99–100%) to Vibrio and E. cloacae strains using phylogenetic analysis of 16S rRNA. Most isolates exhibited sensitivity to florfenicol, ciprofloxacin, and norfloxacin, while they were resistant to erythromycin and amoxicillin. Hemorrhage, oedema, hemosiderosis, and melanomacrophage activation in most affected tissues of infected M. cephalus were detected by light microscopy. Nevertheless, higher levels of AST and ALT, as well as serum inflammatory markers, CRP, and lysozyme activity, were shown in infected fish. There were higher MDA levels, along with a reduction of GSH, SOD, and catalase, in the gills and brain of infected M. cephalus, compared to the control fish. Our obtained data confirmed the high prevalence of Vibrio serovars and E. cloacae in infected grey mullets, describing their histopathological alterations, higher inflammatory response, and oxidative stress impact. These results could be useful indicators for understanding the pathogenesis of these pathogens in correlation with water parameter deterioration. Thus, the emergence of Vibrio and E. cloacae species in this study threatens the brackish water aquaculture industry in Egypt and poses a public health concern.

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Comparative immunomodulatory effects in mice and in human dendritic cells of five bacterial strains selected for biocontrol of leafy green vegetables

Cited by 2 publications

References 33 publications

Cold plasma application to fresh green leafy vegetables: Impact on microbiology and product quality

Cold plasma application to fresh green leafy vegetables: Impact on microbiology and product quality

Bacterial Co-Infection as a Potential Threat to Farmed Flathead Grey Mullet (Mugil cephalus): Phenotypic and Molecular Diagnosis, Histopathology, Immunity Response, and In Vitro Antibacterial Evaluation

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