Abstract:Objective:an immunohistochemical analysis of the features of expression, distribution and interaction of E-сadherin and β-сatenin proteins in primary mammary tumors.Materials and methods.The study group consisted of 148 relevant patients with breast cancer (BC), including patients with metastases in lymph nodes (n = 12) and liver (n = 45). E-сadherin and β-сatenin expression on BC cells was determined using immunohistochemical method with specific antibodies.Results.It was shown that the reduction and the tota… Show more
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