Comparative Genomics and Transcriptomics Analyses Reveal a Unique Environmental Adaptability of Vibrio fujianensis

Abstract

The genus Vibrio is ubiquitous in marine environments and uses numerous evolutionary characteristics and survival strategies in order to occupy its niche. Here, a newly identified species, Vibrio fujianensis, was deeply explored to reveal a unique environmental adaptability. V. fujianensis type strain FJ201301T shared 817 core genes with the Vibrio species in the population genomic analysis, but possessed unique genes of its own. In addition, V. fujianensis FJ201301T was predicated to carry 106 virulence-related factors, several of which were mostly found in other pathogenic Vibrio species. Moreover, a comparative transcriptome analysis between the low-salt (1% NaCl) and high-salt (8% NaCl) condition was conducted to identify the genes involved in salt tolerance. A total of 913 unigenes were found to be differentially expressed. In a high-salt condition, 577 genes were significantly upregulated, whereas 336 unigenes were significantly downregulated. Notably, differentially expressed genes have a significant association with ribosome structural component and ribosome metabolism, which may play a role in salt tolerance. Transcriptional changes in ribosome genes indicate that V. fujianensis may have gained a predominant advantage in order to adapt to the changing environment. In conclusion, to survive in adversity, V. fujianensis has enhanced its environmental adaptability and developed various strategies to fill its niche.

Vibriosis Outbreaks in Aquaculture: Addressing Environmental and Public Health Concerns and Preventive Therapies Using Gilthead Seabream Farming as a Model System

“…The first Vibrio species described was Vibrio cholerae , in 1854, in the context of a study on cholera outbreaks in Florence (Thompson et al, 2004 ), but there are records of cholera-like diseases occurring in the times of Hippocrates (460–377 BC) (Blake, 1994 ). Currently, more than 130 species grouped in 14 clades in the Vibrio genus are recognized (Romalde et al, 2014 ; Huang et al, 2020 ), including commensal, mutualistic, and pathogenic species (Thompson et al, 2004 ).…”

Probing the physiological roles of the extracellular loops of chitoporin from Vibrio campbellii

“…where [q] is molar ellipticity in deg,cm 2 ,dmol À1 , n is the number of amino acids in the polypeptide chain, m is the measured ellipticity, and l cm is the path length in centimeters (40,41). The intensity of standard CSA (non-hygroscopic ammonium (þ)-10-camphorsulphonate) at 290 nm is approximately 45 units, giving the calculated conversion factor from 3300/CSA intensity to be 73.33.…”

“…Vibrio spp. are highly abundant in marine habitats, with more than 130 species being identified to date (2). The rising populations of Vibrio spp.…”

Population Analysis of Vibrio cholerae in Aquatic Reservoirs Reveals a Novel Sister Species ( Vibrio paracholerae sp. nov.) with a History of Association with Humans

“…However, there are parts of the O antigen region in V. cholerae reference O139 strain MO10 (designated region IV by Yamasaki et al) for which the origin could not be attributed to either O22 or V. cholerae O1 ( 54 ). Recently, closely related homologs of genes in region IV of V. cholerae O139 strains were found in V. fujianensis ( 55 ). This indicates that the origin of the MO10 O antigen region is most likely a result of multiple recombination events from various origins, forming the mosaic O antigen-encoding region in V. cholerae O139.…”