Comparative evaluation of topical application of turmeric gel and 0.2% chlorhexidine gluconate gel in prevention of gingivitis

Singh, Vibha; Pathak, Anjani Kumar; Pal, Mahesh; Sareen, Sagar; Goel, Kopal

doi:10.4103/0975-5950.168238

Cited by 20 publications

(19 citation statements)

References 9 publications

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“…The mean PI, GI and PPD in both the groups decrease after the treatment, and the decrease was more evident in Group II (Vajradanti) than Group I. Similar studies have been done previously with herbs like turmeric where the authors have evaluated the effect of turmeric on clinical parameters using the PI, GI, and PPD and found that turmeric gel can be effectively used as an adjunct to mechanical plaque control in the prevention of plaque and gingivitis [7].…”

Section: Discussionsupporting

confidence: 61%

Evaluation of Topical Application of Vajradanti Gel in Prevention of Gingivitis

Pathak¹,

Singh²,

Pal³

et al. 2017

OJST

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Vajradanti means strong teeth in Hindi. The medicinal properties of Vajradanti plant are well reported in Ayurveda. Its botanical name is Barleria prionitis L. and it belongs to family Acanthaecae. The use of herbal products in the field of medicine has gained popularity in recent years. In India, herbal plants are used as a regular source of medicine. Plants, such as Turmeric, Ashoka and Triphala, are some common household names being widely used nowadays. One such name is Barleria prionitis L. or Vajradanti, having antiarthritic, anti-inflammatory and anti-fertility properties. The leaves of this flower are also believed to provide relief in tooth ache. So these properties lead us to the use of this shrub in the remedy of dental diseases. Materials and Methods: The study was conducted in the Department of Periodontology, in collaboration with the Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King George's Medical University, Lucknow, India and N.B.R.I. Lucknow. A total of 80 subjects, from age group 20 -50 years, were selected. The study unit consisted of patients of chronic gingivitis. Simple random sampling, utilizing computer generated random numbers, was employed to assign the participants to two groups, "I" and "II", each having 40 participants. In patients of Group-I scaling and root planing was performed, whereas in patients of Group-II, scaling and root planing was performed and subjects were advised to apply Vajradanti gel twice daily after brushing. Statistical Analysis: Data were summarized as mean ± SD. Pre and post outcome results of two groups were compared by the paired t-test. Conclusions: Based on the observations and results of our study, it can be concluded that scaling and root planing remains the gold standard for the treatment of gingival and periodontal diseases while the Vajradanti gel (Barleria prionitis L.) can be effectively used as an adjunct to mechanical plaque control in prevention of 106chronic gingivitis. The beneficial effect of Vajradanti can be attributed to its anti inflammatory properties.

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Section: Discussionsupporting

confidence: 61%

Evaluation of Topical Application of Vajradanti Gel in Prevention of Gingivitis

Pathak¹,

Singh²,

Pal³

et al. 2017

OJST

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“…However, our results differ from Singh et al . 2015,[ 23 ] wherein reduction in PI at end of 2 nd and 3 rd week was better in CHX group. Similarly, the decrease of mean GI was evidently higher in Group CHX than Group CMN.…”

Section: Discussionmentioning

confidence: 99%

Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study

Arunachalam¹,

Sudhakar²,

Vasanth³

et al. 2017

J Indian Soc Periodontol

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Background:To evaluate and compare the effect of curcumin (CMN) mouth rinse with chlorhexidine (CHX) mouth rinse on clinical parameters and reactive oxygen metabolites (ROM) levels in participants with chronic gingivitis.Materials and Methods:Thirty plaque-induced generalized chronic gingivitis participants were randomly assigned to three groups – Group I (control/saline), Group II (CHX), and Group III (CMN), respectively. Baseline plaque index (PI), gingival index (GI), and salivary ROM were estimated, and oral prophylaxis was done. The parameters were recorded and evaluated again at the end of 4 weeks.Results:Overall, the three groups have shown a significant reduction in PI, GI, and ROM levels at the end of 4 weeks. However, on intragroup comparison, only CMN group have shown significant reduction in ROM levels at the end of 4 weeks (P < 0.05).Conclusion:CMN mouth rinse can be considered as an alternative antigingivitis agent to CHX because of its anti-inflammatory and antioxidant properties.

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“…It is even being pursued as a preventative measure and as a treatment for Alzheimer's disease (Mishra and Palanivelu, ; Mori, ). Turmeric oil has been tested against ocular and gingival infection models (Singh et al ., ; Singh et al ., ), with modestly successful results in comparison with contemporary antibiotic therapies. Turmeric and curcumin's efficacy against various infectious organisms likely results from multiple mechanisms; theories include curcumin's ability to perturb bacterial membranes, inhibit replication machinery, change gene expression, and even impair biofilm formation.…”

Section: Introductionmentioning

confidence: 99%

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

Vaughn

Haas

Burney

et al. 2017

Phytotherapy Research

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Turmeric root (Curcuma longa) is predominantly used as a spice, but has also long been known to possess antimicrobial, analgesic, antiinflammatory, and anticancer properties. One predominant group of active compounds in turmeric are curcuminoids, namely bright yellow-pigmented curcumin. While modern science has yet to fully investigate the therapeutic claims of turmeric and its derivatives, results have proven promising in decreasing pain and inflammation in arthritis, improving insulin sensitivity in diabetes, and even curing a variety of infections. The purpose of this review is to discuss the potential for curcumin as an agent against microbial infections, with a special focus on the skin and in the development of bacterial biofilms. Curcumin has demonstrated bactericidal efficacy against a variety of infections when administered with antibiotics in several clinical studies, with consistent antimicrobial activity demonstrated in vitro, as well as in urinary tract infections, gingival infections, and chronic wound infections. Hypothesized mechanisms of action include curcumin's ability to perturb bacterial membranes, disturb protofillament assembly, and even impair bacterial virulence factors. Further investigation is needed to fully understand which organisms are most susceptible to the effects of curcumin and how curcumin can be implemented in dermatology to treat skin conditions such as chronic wounds and acne vulgaris. Copyright © 2017 John Wiley & Sons, Ltd.

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Comparative evaluation of topical application of turmeric gel and 0.2% chlorhexidine gluconate gel in prevention of gingivitis

Cited by 20 publications

References 9 publications

Evaluation of Topical Application of Vajradanti Gel in Prevention of Gingivitis

Evaluation of Topical Application of Vajradanti Gel in Prevention of Gingivitis

Comparison of anti-plaque and anti-gingivitis effect of curcumin and chlorhexidine mouth rinse in the treatment of gingivitis: A clinical and biochemical study

Potential Role of Curcumin Against Biofilm‐Producing Organisms on the Skin: A Review

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