Comparative evaluation of the diagnosis of acute pancreatitis based on serum and urine enzyme assays

Gwozdz, Glenn P.; Steinberg, William M.; Werner, Mario; Henry, James P.; Pauley, Carol

doi:10.1016/0009-8981(90)90109-6

Cited by 49 publications

(25 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12,13 One study demonstrated that at day 0-1 from onset of symptoms, serum lipase had a sensitivity approaching 100% compared with 95% for serum amylase. 13 For days 2-3 at a sensitivity set to 85%, the specificity of lipase was 82% compared with 68% for amylase.…”

Section: Diagnosis Of Acute Pancreatitismentioning

confidence: 99%

“…Serum lipase is also more sensitive than serum amylase in patients with acute pancreatitis secondary to alcohol overuse. 12 Furthermore, simultaneous determination of serum lipase and amylase only marginally improve the diagnosis of acute pancreatitis in patients with acute abdominal pain. 13 Biliary stones and alcohol overuse are the causes of acute pancreatitis in 70%-80% of cases.…”

Section: Diagnosis Of Acute Pancreatitismentioning

confidence: 99%

See 1 more Smart Citation

Clinical practice guideline: management of acute pancreatitis

Greenberg¹,

Hsu²,

Bawazeer³

et al. 2016

cjs

326

352

View full text Add to dashboard Cite

There has been an increase in the incidence of acute pancreatitis reported worldwide. Despite improvements in access to care, imaging and interventional techniques, acute pancreatitis continues to be associated with significant morbidity and mortality. Despite the availability of clinical practice guidelines for the management of acute pancreatitis, recent studies auditing the clinical management of the condition have shown important areas of noncompliance with evidence-based recommendations. This underscores the importance of creating understandable and implementable recommendations for the diagnosis and management of acute pancreatitis. The purpose of the present guideline is to provide evidence-based recommendations for the management of both mild and severe acute pancreatitis as well as the management of complications of acute pancreatitis and of gall stone-induced pancreatitis.Une hausse de l'incidence de pancréatite aiguë a été constatée à l'échelle mondiale. Malgré l'amélioration de l'accès aux soins et aux techniques d'imagerie et d'intervention, la pancréatite aiguë est toujours associée à une morbidité et une mortalité importantes. Bien qu'il existe des guides de pratique clinique pour la prise en charge de la pancréatite aiguë, des études récentes sur la vérification de la prise en charge clinique de cette affection révèlent des lacunes importantes dans la conformité aux recommandations fondées sur des données probantes. Ces résultats mettent en relief l'importance de formuler des recommandations compréhensibles et applicables pour le diagnostic et la prise en charge de la pancréatite aiguë. La présente ligne directrice vise à fournir des recommandations fondées sur des données probantes pour la prise en charge de la pancréatite aiguë, qu'elle soit bénigne ou grave, ainsi que de ses complications et de celles de la pancréatite causée par un calcul biliaire.A cute pancreatitis can range from a mild, self-limiting disease that requires no more than supportive measures to severe disease with lifethreatening complications. The most common causes of acute pan creatitis are gallstones and binge alcohol consumption.1 There has been an increase in the incidence of acute pancreatitis reported worldwide. Despite improvements in access to care, imaging and interventional techniques, acute pancreatitis continues to be associated with significant morbidity and mortality.A systematic review of clinical practice guidelines for the management of acute pancreatitis revealed 14 guidelines published between 2004 and 2008 alone.2 Although these guidelines have significant overlap in their recommendations for diagnosing and managing acute pancreatitis, there is disagreement in some aspects of both the timing and types of interventions that should be used for both mild and severe acute pancreatitis. The availability of new imaging modalities and noninvasive therapies has also changed clinical practice. Finally, despite the availability of guidelines, recent studies auditing clinical management of acute pancreatitis have sh...

show abstract

Section: Diagnosis Of Acute Pancreatitismentioning

confidence: 99%

Section: Diagnosis Of Acute Pancreatitismentioning

confidence: 99%

Clinical practice guideline: management of acute pancreatitis

Greenberg¹,

Hsu²,

Bawazeer³

et al. 2016

cjs

326

352

View full text Add to dashboard Cite

show abstract

“…Serum lipase is always elevated on the first day of illness and remains elevated longer than the serum amylase. 6 Serum lipase amylase ratio can be a useful marker for predicting aetiology of acute pancreatitis. Devanath et al (2009) showed that the sensitivity and specificity to predict alcoholic acute pancreatitis with lipase-amylase ratio at >4 was 84% and 59% respectively.…”

Section: Introductionmentioning

confidence: 99%

Serum Lipase Amylase Ratio in Predicting Aetiology, Severity and Outcome of Acute Pancreatitis in a Tertiary Care Hospital

Haque

Azam

Sarkar

et al. 2017

Bangladesh Crit Care J

View full text Add to dashboard Cite

“…Serum lipase is normal when serum amylase is elevated, as in salivary gland dysfunction, tumours, gynaecologic conditions, and macroamylasemia. Serum lipase is always elevated on the 1st day of illness and remains elevated longer than does the serum amylase, thus having a higher sensitivity 10 . Specificity of lipase can suffer from some of the same problems as those of amylase.…”

Section: Introductionmentioning

confidence: 99%