Comparative evaluation of in vivo relative bioavailability and in vitro bioaccessibility of arsenic in leafy vegetables and its implication in human exposure assessment

Zheng, Xiaoman; Zhang, Zengyu; Chen, Jiancheng; Liang, Huanting; Xue, Chen; Qin, Yan; Shohag, M. J. I.; Wei, Yanyan; Gu, Minghong

doi:10.1016/j.jhazmat.2021.126909

Cited by 40 publications

(9 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nowadays, exploring the prevention and control methods to combat As pollution is a hot topic in the interdisciplinary research of agricultural environment and biology (Dong et al, 2021;Zheng et al, 2022). Selenium (Se) is one of the essential nutrients and plays an essential physiological function in the human body.…”

Section: Determination Of Chlorophyll and Malondialdehyde Contentmentioning

confidence: 99%

Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress

Wang

Zou

et al. 2022

Ital. J. Food Sci.

View full text Add to dashboard Cite

Arsenic (As) pollution, a potential threat for human health, in vegetables is one of the primary sources of As intake by the human body. In the Pot Experiment, the As content, physiological index and antioxidant enzyme activity of radish were determined. The results demonstrated that the order of As concentration in radish tissues was roots > stems > leaves. Organic selenium (Se) can inhibit the absorption of arsenic in radish more effectively than inorganic Se. The application of organic Se and low concentration of selenite (Se(IV)) significantly enhanced the stress resistance of radish for increasing superoxide dismutase and peroxidase activity, increasing soluble protein, chlorophyll and proline content, and reducing malondialdehyde content. In contrast, the high concentration of Se(IV) and selenate (Se(VI)) treatment group demonstrated stress and toxicological effects on radish. This study provides an idea for further research on the remediation mechanism of Se to As toxicity and provides a reference for the adoption of Se fertilizer in agriculture.

show abstract

Section: Determination Of Chlorophyll and Malondialdehyde Contentmentioning

confidence: 99%

Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress

Wang

Zou

et al. 2022

Ital. J. Food Sci.

View full text Add to dashboard Cite

show abstract

“…Furthermore, As levels in 96% of the flowering cabbages were lower than the Chinese National Standards' (GB 2762-2017) tolerance limit (0.50 mg/kg) for pollutants in foods (Chang et al, 2022). Zheng et al (2022) found a wide range of total As concentration in vegetable samples (0.52-15.94 mg/kg dry weight; mean: 6.55 ± 5.18 mg/kg dry weight) from samples collected from As-polluted farmlands, which were attributed to anthropogenic activities in Guangxi province, China. The highest As concentrations were found in Romaine lettuce (15.94 mg/kg dry weight), leaf lettuce (10.48 mg/kg dry weight), and leaf mustard (11.10 mg/kg dry weight).…”

Section: Comparatively Higher Levels Of As In Centella Asiatica With ...mentioning

confidence: 86%

Ecological–Health Risk of Antimony and Arsenic in Centella asiatica, Topsoils, and Mangrove Sediments: A Case Study of Peninsular Malaysia

Yap

Tan²,

Cheng³

et al. 2022

Front. Environ. Sci.

View full text Add to dashboard Cite

The current study assessed the ecological–health risks of potentially toxic arsenic (As) and antimony (Sb) in the vegetable Centella asiatica, topsoils, and mangrove sediments sampled from Peninsular Malaysia. The As concentrations ranged from 0.21 to 4.33, 0.18 to 1.83, and 1.32 to 20.8 mg/kg dry weight, for the leaves, stems, and roots of the vegetable, respectively. The ranges of Sb concentrations were 0.31–0.62, 0.12–0.35, and 0.64–1.61 mg/kg dry weight, for leaves, stems, and roots of the vegetable, respectively. The children’s target hazard quotient (THQ) values indicated no non-carcinogenic risks of As and Sb in both leaves and stems, although children’s THQ values were higher than those in adults. The calculated values of estimated weekly intake were lower than established provisional tolerable weekly intake of As and Sb for both children and adult consumers. The carcinogenic risk (CR) values of As for children’s intake of leaves and stems of vegetables showed more public concern than those of adults. The levels of Sb and As in the topsoils were generally higher (although not significantly) than those in the mangrove sediments, resulting in a higher geoaccumulation index, contamination factor and ecological risk, hazard index, THQ, and CR values. This indicated that the anthropogenic sources of Sb and As originated from the land-based activities before reaching the mangrove near the coast. The CR of As signifies a dire need for comprehensive ecological–health risks exposure studies, as dietary intake involves more than just vegetable consumption. Therefore, risk management for As and Sb in Malaysia is highly recommended. The present findings of the ecological–health risks of As and Sb based on 2010–2012 samples can be used as an important baseline for future reference and comparison.

show abstract

“…For example, copper (Cu) and zinc (Zn) are essential trace elements for human bodies, but excessive intake can be toxic [ 2 ]. Arsenic (As) is a toxic trace element that raises concerns related to human health [ 3 , 4 ]. In recent decades, environmental pollution has become more serious, which could potentially result in excessive intake of trace elements from the diet [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Culinary Procedures on Concentrations and Bioaccessibility of Cu, Zn, and As in Different Food Ingredients

Zhang

Miao

et al. 2023

Foods

View full text Add to dashboard Cite

Although cooked diets are the primary sources for humans to absorb trace elements, there is limited data available on the concentrations and bioaccessibility of trace elements in cooked food ingredients. This work aims to evaluate the effects of culinary procedures on the concentrations and bioaccessibility of trace elements in common food ingredients. Twelve food species from the local market were treated with four culinary procedures (boiling, steaming, baking, and frying), then the bioaccessibility of copper (Cu), zinc (Zn), and arsenic (As) were evaluated using the in vitro digestion method. The subcellular distribution of these elements was also determined using the sequential fractionation method. The results show that culinary procedures decreased the retention rate of As during cooking (100% for raw and 65–89% for cooked ingredients) and the bioaccessibility of Cu and Zn during digestion (nearly 75% for raw and 49–65% for cooked ingredients), resulting in a reduction of the total bioaccessible fraction (TBF) of Cu, Zn, and As in food ingredients. The TBF of Cu, Zn, and As in all tested food ingredients followed the order: raw (76–80%) > steaming and baking (50–62%) > boiling and frying (41–50%). The effects of culinary procedures were associated with the subcellular distribution of trace elements. As was dominantly distributed in heat-stable proteins (51–71%), which were more likely to be lost during cooking. In comparison, Cu and Zn were mainly bound to the insoluble fraction and heat-denatured proteins (60–89% and 61–94% for Cu and Zn, respectively), which become less digestible in cooked ingredients. In conclusion, these results suggest that culinary procedures reduce the absorption of Cu, Zn, and As in various food ingredients, which should be considered in the coming studies related to nutrition and risk assessment of trace elements.

show abstract

Comparative evaluation of in vivo relative bioavailability and in vitro bioaccessibility of arsenic in leafy vegetables and its implication in human exposure assessment

Cited by 40 publications

References 71 publications

Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress

Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress

Ecological–Health Risk of Antimony and Arsenic in Centella asiatica, Topsoils, and Mangrove Sediments: A Case Study of Peninsular Malaysia

Effects of Culinary Procedures on Concentrations and Bioaccessibility of Cu, Zn, and As in Different Food Ingredients

Contact Info

Product

Resources

About