Comparative Evaluation of Bioinformatic Pipelines for Full-Length Viral Genome Assembly
Levente Zsichla,
Marius Zeeb,
Dávid Fazekas
et al.
Abstract:The increasingly widespread application of next-generation sequencing (NGS) in clinical diagnostics and epidemiological research has generated a demand for robust, fast, automated, and user-friendly bioinformatic workflows. To guide the choice of tools for the assembly of full-length viral genomes from NGS datasets, we assessed the performance and applicability of four widely adopted bioinformatic pipelines (shiver - for which we created a user-friendly Dockerized version, referred to as dshiver; SmaltAlign, v… Show more
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