Comparative efficacy of xylanases on growth performance and digestibility in growing pigs fed wheat and wheat bran- or corn and corn DDGS-based diets supplemented with phytase

Ndou, Saymore Petros; Kiarie, E.; Agyekum, A. K.; Heo, Jung Min; Romero, L. F.; Arent, S.; Lorentsen, Rikke Høegh; Nyachoti, C. M.

doi:10.1016/j.anifeedsci.2015.08.011

Cited by 54 publications

(51 citation statements)

References 30 publications

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“… Zeng et al (2018) recently reported that addition of an enzyme blend (galactanase, xylanase, mannanase, α-amylase, and cellulase) improved AID, but not ATTD, of energy, NDF, and nonstarch polysaccharides ( NSP ) constituents in wheat bran containing diets. This indicates that enzyme supplementation may shift fiber degradation from the hindgut to the small intestine, which is supported by Ndou et al (2015) and Moran et al (2016) . Energy absorbed in the small intestine will be used by the pig with greater efficiency than if it is released by fermentation in the lower gut ( Patience, 2017 ).…”

Section: Discussionmentioning

confidence: 74%

“…The objective of most of these studies has been to improve the nutritional value of higher fiber diets for pork production ( Nortey et al, 2008 ; Passos et al, 2015 ). Because older pigs generally have greater digestive capacity to utilize dietary fiber than young piglets, most research has focused on evaluating the effects of carbohydrases in growing or finishing pigs fed diets high in coproducts ( Jacela et al, 2010 ; Kiarie et al, 2012 ; Ndou et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

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A dietary carbohydrase blend improved intestinal barrier function and growth rate in weaned pigs fed higher fiber diets1

Gabler

Loving

et al. 2018

Journal of Animal Science

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The objective of this study was to evaluate the effects of dietary xylanase (X) and a carbohydrase enzyme blend (EB: cellulase, β-glucanase, and xylanase) on nutrient digestibility, intestinal barrier integrity, inflammatory status, and growth performance in weaned piglets fed higher fiber diets. A total of 460 pigs (6.43 ± 0.06 kg BW; F25 × 6.0 Genetiporc) were blocked by initial BW and pens (n = 12 per treatment) were randomly assigned to 1 of 4 dietary treatments. The diets included a higher fiber unsupplemented control diet (CON) and the CON supplemented with 0.01% X, 0.01% EB, or both enzymes, arranged in a 2 × 2 factorial. The diets were based on corn, soybean meal, corn distillers dried grains with solubles (DDGS), and wheat middlings. Pigs had 7 d to adapt to the environment and consumed the same commercial diet. Pigs were fed the experimental diets for 28 d with free access to feed and water. Body weight and feed disappearance were recorded weekly. One pig with BW closest to the pen average from each pen was selected and moved to metabolism crates on day 16 and intragastric gavaged a solution of lactulose and mannitol on day 22 followed by 12-h urine collection. Feces were collected from day 23 to 25. Intestinal tissues and mucosal scrapings were collected on day 28. Data were analyzed using PROC MIXED of SAS (9.4). Xylanase, EB, and their interaction were fixed effects and block was a random effect. The EB, but not X, increased pig BW and improved ADG over 28 d (P < 0.05). Neither carbohydrase impacted ADFI, G:F, or apparent total tract digestibility (ATTD) of DM, GE, or CP. The EB improved ATTD of ADF (32.45 vs. 26.57%; P < 0.01), but had no effect on NDF. Unexpectedly, X reduced ATTD of NDF and ADF (P < 0.01). The EB reduced urinary lactulose:mannitol and increased ileal claudin-3 mRNA abundance (P < 0.05), indicating improved small intestinal barrier integrity. There was a X × EB interaction on ileal secretory immunoglobulin A (sIgA) concentration (P < 0.05); in the absence of X, EB decreased sIgA compared to CON, but this effect disappeared in the presence of X. The EB also reduced ileal IL-22 mRNA abundance (P < 0.05), probably indicating decreased immune activation. In conclusion, EB but not X enhanced growth rate of weaned pigs fed higher fiber diets, which may be partly explained by the improved small intestinal barrier integrity and reduced immune activation, rather than improvement in nutrient digestibility.

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 99%

A dietary carbohydrase blend improved intestinal barrier function and growth rate in weaned pigs fed higher fiber diets1

Gabler

Loving

et al. 2018

Journal of Animal Science

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“…The coefficient of apparent total tract digestibility (CATTD) of fat was calculated relative to TiO 2 concentration, as described by Ndou et al . 70 .…”

Section: Methodsmentioning

confidence: 99%

Dietary supplementation with flaxseed meal and oat hulls modulates intestinal histomorphometric characteristics, digesta- and mucosa-associated microbiota in pigs

Ndou

Tun

Kiarie

et al. 2018

Sci Rep

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The establishment of a healthy gastrointestinal milieu may not only offer an opportunity to reduce swine production costs but could also open the way for a lifetime of human health improvement. This study investigates the effects of feeding soluble fibre from flaxseed meal-containing diet (FM) and insoluble fibre from oat hulls-containing diet (OH) on histomorphological characteristics, digesta- and mucosa-associated microbiota and their associations with metabolites in pig intestines. In comparison with the control (CON) and OH diets, the consumption of FM increased (P < 0.001) the jejunal villi height (VH) and the ratio of VH to crypt depths. The PERMANOVA analyses showed distinct (P < 0.05) microbial communities in ileal digesta and mucosa, and caecal mucosa in CON and FM-diets fed pigs compared to the OH diet-fed pigs. The predicted functional metagenomes indicated that amino acids and butanoate metabolism, lysine degradation, bile acids biosynthesis, and apoptosis were selectively enhanced at more than 2.2 log-folds in intestinal microbiota of pigs fed the FM diet. Taken together, flaxseed meal and oat hulls supplementation in growing pigs’ diets altered the gastrointestinal development, as well as the composition and function of microbial communities, depending on the intestinal segment and physicochemical property of the dietary fibre source.

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“…In a preliminary study, optimal pH for the activity of xylanase with fungal and bacterial origin was determined as described by Gomes et al (2013), and it was 4-5 for bacterial and 6-7 for fungal originated xylanase, respectively. Furthermore, these enzymes showed more than 80% recovery in the test of proteolytic stability against pepsin at pH ¼ 2 and 3 according to the method of Ndou et al (2015).…”

Section: Enzyme Preparationmentioning

confidence: 99%

Productive performance, nutrient digestibility and intestinal morphometry in broiler chickens fed corn or wheat-based diets supplemented with bacterial- or fungal-originated xylanase

Ghayour-Najafabadi

Khosravinia

Gheisari

et al. 2017

Italian Journal of Animal Science

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An experiment was conducted to evaluate effects of dietary supplementation of a corn-or a wheat-based diet with two sources of exogenous xylanase (fungal or bacterial originated) on productive performance, ileal nutrients digestibility, nitrogen-corrected apparent metabolisable energy (AME n ) and digestive organs morphometry in broiler chickens. Broilers were fed with one of the six dietary treatments consisting of two basal diets (based on corn or wheat) each with or without xylanase (from bacterial or fungal origin) supplementation. Compared with corn-based diet, feeding birds with the wheat-based diet improved weight gain and feed intake by 4.71 and 4.81%, respectively, and ileal digestibility of dry matter and crude protein were greater in birds fed wheat-based diets compared with the birds grown on corn-based during Days 1-21 of age (p<.05). Villus length and villus length to crypt depth ratio increased (p < .05) in birds received wheat-based diets compared with those fed on corn-based diets. Gizzard weight was greater in birds fed with corn-based diets on days 21 and 42 of age by 11.5% and 31.8%, respectively, compared with those received wheat-based diets (p < .05). Supplementing diets with fungal xylanase increased liver weight in birds grown on wheat-based diets compared with those grown on control and corn-based diets, respectively, on Days 21 and 42 of age (p < .05). It was concluded that supplementing a corn-or wheat-based diet with a xylanase of bacterial or fungal origin had no effect on productive performance or AMEn of diets in broiler chickens during the starter and growing periods. ARTICLE HISTORY

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Comparative efficacy of xylanases on growth performance and digestibility in growing pigs fed wheat and wheat bran- or corn and corn DDGS-based diets supplemented with phytase

Cited by 54 publications

References 30 publications

A dietary carbohydrase blend improved intestinal barrier function and growth rate in weaned pigs fed higher fiber diets1

A dietary carbohydrase blend improved intestinal barrier function and growth rate in weaned pigs fed higher fiber diets1

Dietary supplementation with flaxseed meal and oat hulls modulates intestinal histomorphometric characteristics, digesta- and mucosa-associated microbiota in pigs

Productive performance, nutrient digestibility and intestinal morphometry in broiler chickens fed corn or wheat-based diets supplemented with bacterial- or fungal-originated xylanase

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