Comparative Efficacy of Nebulized L-adrenaline versus Salbutamol in Infants with Acute Bronchiolitis

Morshed, Akm Amirul; Amin, Muhammad Umar

doi:10.3329/bjch.v32i1.6007

Cited by 2 publications

(5 citation statements)

References 12 publications

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“…Almost similar percentage of patients in both groups presented with fever (up to 101°F). Two studies from Bangladesh observed the same clinical patterns similar to our study 5,9 .…”

Section: Resultssupporting

confidence: 90%

“…Another study of 703 children with bronchiolitis compared 3 doses of albuterol with 1 dose of racemic epinephrine and revealed a small benefit that favored albuterol in successful discharge. 12 In a study, both nebulized salbutamol and adrenaline were useful in relieving symptoms & improving oxygenation, but comparatively nebulized adrenaline was superior to nebulized salbutamol in bronchiolitis 9 .…”

Section: Resultsmentioning

confidence: 99%

“…Medical therapies used to treat bronchiolitis in infants and young children are controversial 11 . Although numerous medications and interventions have been used to treat bronchiolitis, at present, only oxygen appreciably improves the condition of young children with bronchiolitis 9 . Bronchodilatorsare commonly used in practice, though convincing evidence is absent.…”

Section: Resultsmentioning

confidence: 99%

“…Hypoxia is the best predictor of severe illness and correlates best with the degree of tachypnea. No routine diagnostic tests except for pulse oxymetry, have been shown to have a substantial impact on the clinical course of bronchiolitis, and recent guidelines and evidence-based reviews recommend that no diagnostic tests are used routinely 5,9 . Tests are typically used to exclude other diagnoses (eg, bacterial pneumonia, sepsis, or congestive heart failure) or to confirm a viral etiology 10 .…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Audit on the Management of Bronchiolitis: A Single Centre Real World Experience in Bangladesh Can We do Better ?

Hamid

Quaium

Rahman

et al. 2015

Chatt Maa Shi Hosp Med Coll J

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Background: Bronchiolitis is the most common reason for hospitalization of children in many countries.Though Respiratory Syncytial Virus (RSV) is the most common organism causing bronchiolitis, but antibiotics are used widely.So the aim of the present study is to establish whether antibiotic has any role in bronchiolitis management along with supportive treatment. Methods:This retrospective study included 100 infants and children between 2-24 months of age admitted with clear cut sign symptoms of bronchiolitis. Patients were divided into Group A (supportive + antibiotic Rx) comprised 72 patients and group B (supportive Rx only) comprised 28 patients.After 3-5 days of hospital stay, clinical responses were evaluated in terms of improvement in symptoms and clinical parameters-respiratory rate, heart rate and oxygen saturation.

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“…Almost similar percentage of patients in both groups presented with fever (up to 101°F). Two studies from Bangladesh observed the same clinical patterns similar to our study 5,9 .…”

Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Audit on the Management of Bronchiolitis: A Single Centre Real World Experience in Bangladesh Can We do Better ?

Hamid

Quaium

Rahman

et al. 2015

Chatt Maa Shi Hosp Med Coll J

View full text Add to dashboard Cite

show abstract

“…This study showed that mean respiratory rate (52.5±4.9 vs. 50±2.9, P<0.05), oxygen saturation (97.1±1.5 vs. 97.9±0.8, P<0.05), mean heart rate (151.8±10 vs 160.2±10.2, P<0.05) and RDAI score (6.4±1.7 vs. 7.7±1.0, p>0.05) were significantly different in salbutamol and nebulized adrenaline therapy, respectively for management of bronchiolitis in children. 7 But another trial concluded that nebulized epinephrine was not found to be more efficacious than albuterol in treating moderately ill infants with bronchiolitis. 8 Adhikari et al, reported that mean respiratory rate (37.0±6.0 vs. 36.0±5.0) and RDAI score (4.15±1.82 vs. 4.1±1.36) were significantly different in salbutamol and nebulized adrenaline therapy, respectively for management of bronchiolitis in children.…”

Section: Methodsmentioning

confidence: 99%

Nebulized epinephrine versus salbutamol for the management of children presenting with bronchiolitis: Single Center Study.

Farooq

Maqbool

Aslam

et al. 2020

TPMJ

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Objectives: To compare the outcome of nebulized epinephrine versus salbutamol for the management of children presenting with bronchiolitis. Study Design: Randomized Controlled Trial. Setting: Department of Pediatrics, Federal Government Polyclinic Hospital, Islamabad. Period: 6 month (1st October, 2016 to 1st April, 2017). Material & Methods: Children fulfilled selection criteria were enrolled. Then patients were randomly divided in two groups by using lottery method. In Group A, children received salbutamol. In group B, children received nebulized adrenaline. After 48 hours, children were evaluated for heart rate, respiratory rates, oxygen saturation and Respiratory Distress Assessment Index (RDAI) score. All the information was collected using proforma. Data was analyzed using SPSS version 21. Results: The mean age of children was 10.45±6.70 months in epinephrine group and13.07±6.28 months in salbutamol group. There were 29 (52.7%) males & 26 (47.3%) females in both groups. After 48 hours, mean heart rate was 122.58±4.75bpm with epinephrine while 127.87±4.4.44bpm with salbutamol. Mean respiratory rate was 35.16±3.29bpm with epinephrine while 39.84±3.32bpm with salbutamol. Mean RDAI score was 8.35±1.36 with epinephrine while 10.07±1.37 with salbutamol. Mean oxygen saturation was 85.24±2.74% with epinephrine while 80.38±3.26% with salbutamol. The difference was significant (P<0.05). Conclusion: Thus the nebulized epinephrine was found to be more effective in maintaining heart rate, respiratory rate, oxygen saturation and RDAI score of children as compared to salbutamol.

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Comparative Efficacy of Nebulized L-adrenaline versus Salbutamol in Infants with Acute Bronchiolitis

Cited by 2 publications

References 12 publications

Audit on the Management of Bronchiolitis: A Single Centre Real World Experience in Bangladesh Can We do Better ?

Audit on the Management of Bronchiolitis: A Single Centre Real World Experience in Bangladesh Can We do Better ?

Nebulized epinephrine versus salbutamol for the management of children presenting with bronchiolitis: Single Center Study.

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