Comparative efficacy and acceptability of electroconvulsive therapy versus repetitive transcranial magnetic stimulation for major depression: A systematic review and multiple-treatments meta-analysis

Chen, Jianjun; Zhao, Libo; Liu, Yi-yun; Fan, ST; Xie, Peng

doi:10.1016/j.bbr.2016.11.028

Cited by 98 publications

(56 citation statements)

References 59 publications

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“…A recent meta‐analysis reported that 33.6% and 52% of patients achieved remission after an average of 15.2 rTMS and 8.2 ECT sessions, and the number needed to treat (NNT) was 6 (in favor of ECT) . However, the treatment benefits of ECT need to be weighed against its potential side‐effects and higher treatment‐related cost resultant from hospitalization as ECT is often administered as an inpatient procedure in Singapore. Beyond clinical efficacy, safety, and patient's preference , the comparative cost‐effectiveness can help to inform decisions on resource allocation and treatment utilization.…”

Section: Introductionmentioning

confidence: 99%

Cost-Effectiveness Modeling of Repetitive Transcranial Magnetic Stimulation Compared to Electroconvulsive Therapy for Treatment-Resistant Depression in Singapore

Zhao¹,

Tor

Khoo³

et al. 2018

Neuromodulation: Technology at the Neural Interface

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Section: Introductionmentioning

confidence: 99%

Cost-Effectiveness Modeling of Repetitive Transcranial Magnetic Stimulation Compared to Electroconvulsive Therapy for Treatment-Resistant Depression in Singapore

Zhao¹,

Tor

Khoo³

et al. 2018

Neuromodulation: Technology at the Neural Interface

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“…The mechanisms associated with the pathogenesis of MDD have yet to be completely understood, and the current treatments remain ineffective in a large subset of patients 2,3. To date, the most consistent findings across studies about MDD might be the disproportionate prevalence in women 4.…”

Section: Introductionmentioning

confidence: 99%

Novel urinary metabolite signature for diagnosing postpartum depression

Lin

Chen

Liu

2017

NDT

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BackgroundPostpartum depression (PPD) could affect ~10% of women and impair the quality of mother–infant interactions. Currently, there are no objective methods to diagnose PPD. Therefore, this study was conducted to identify potential biomarkers for diagnosing PPD.Materials and methodsMorning urine samples of PPD subjects, postpartum women without depression (PPWD) and healthy controls (HCs) were collected. The gas chromatography-mass spectroscopy (GC-MS)-based urinary metabolomic approach was performed to characterize the urinary metabolic profiling. The orthogonal partial least-squares-discriminant analysis (OPLS-DA) was used to identify the differential metabolites. The logistic regression analysis and Bayesian information criterion rule were further used to identify the potential biomarker panel. The receiver operating characteristic curve analysis was conducted to evaluate the diagnostic performance of the identified potential biomarker panel.ResultsTotally, 73 PPD subjects, 73 PPWD and 74 HCs were included, and 68 metabolites were identified using GC-MS. The OPLS-DA model showed that there were 22 differential metabolites (14 upregulated and 8 downregulated) responsible for separating PPD subjects from HCs and PPWD. Meanwhile, a panel of five potential biomarkers – formate, succinate, 1-methylhistidine, α-glucose and dimethylamine – was identified. This panel could effectively distinguish PPD subjects from HCs and PPWD with an area under the curve (AUC) curve of 0.948 in the training set and 0.944 in the testing set.ConclusionThese results demonstrated that the potential biomarker panel could aid in the future development of an objective diagnostic method for PPD.

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“…Second, only three studies were used to analyze the side effects; hence, future studies are needed to further assess the safety of the MIS+LMHT. Third, the target temperature and treatment time of LMHT were not consistent, but there were also the general problems for meta-studies to solve 53,54…”

Section: Limitationsmentioning

confidence: 99%

Local mild hypothermia therapy as an augmentation strategy for minimally invasive surgery of hypertensive intracerebral hemorrhage: a meta-analysis of randomized clinical trials

Han¹,

Sheng²,

Su³

et al. 2016

NDT

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BackgroundPrevious studies reported that the mild hypothermia therapy (MHT) could significantly improve the clinical outcomes for patients with hypertensive intracerebral hemorrhage (HICH). Therefore, this meta-analysis was conducted to systematically assess whether the addition of local MHT (LMHT) could significantly improve the efficacy of minimally invasive surgery (MIS) in treating HICH.MethodsRandomized clinical trials on the combined application of MIS and LMHT (MIS+LMHT) vs MIS alone for treating HICH were searched up to September 2016 in databases. Response rate and mortality rate were the primary outcomes, and the neurologic function and Barthel index were the secondary outcomes. Side effects were also analyzed.ResultsTotally, 28 studies composed of 2,325 patients were included to compare the efficacy of MIS+LMHT to MIS alone. The therapeutic effects of MIS+LMHT were significantly better than MIS alone. The pooled odds ratio of response rate and mortality rate was 2.68 (95% confidence interval [CI]=2.22–3.24) and 0.43 (95% CI=0.32–0.57), respectively. In addition, the MIS+LMHT led to a significantly better improvement in the neurologic function and activities of daily living. The incidence of pneumonia was similar between the two treatment methods.ConclusionThese results indicated that compared to MIS alone, the MIS+LMHT could be more effective for the acute treatment of patients with HICH. This treatment modality should be further explored and optimized.

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Comparative efficacy and acceptability of electroconvulsive therapy versus repetitive transcranial magnetic stimulation for major depression: A systematic review and multiple-treatments meta-analysis

Cited by 98 publications

References 59 publications

Cost-Effectiveness Modeling of Repetitive Transcranial Magnetic Stimulation Compared to Electroconvulsive Therapy for Treatment-Resistant Depression in Singapore

Cost-Effectiveness Modeling of Repetitive Transcranial Magnetic Stimulation Compared to Electroconvulsive Therapy for Treatment-Resistant Depression in Singapore

Novel urinary metabolite signature for diagnosing postpartum depression

Local mild hypothermia therapy as an augmentation strategy for minimally invasive surgery of hypertensive intracerebral hemorrhage: a meta-analysis of randomized clinical trials

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