Comparative Effects of Gamma-rays and Electron Beams on Peroxide Formation in Phosphatidylcholine

Todoriki, Setsuko; Hayashi, Toru

doi:10.1271/bbb.58.737

Cited by 2 publications

(1 citation statement)

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“…While most commercial food irradiation and radiation sterilization are conducted with Co‐60 gamma rays, electron beams generated by electron accelerators are increasingly being utilized for treating food and medical products. The dose rates of electron beams are 10 3 to 10 6 times higher than those of gamma rays (Todoroki & Hayashi, ). If a dosimeter is to be used at different irradiation facilities, it is necessary that the response of the dosimeter is independent of dose rates.…”

Section: Resultsmentioning

confidence: 99%

Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation

Menon

Singh

Kadam

et al. 2019

J Food Process Preserv

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Optically stimulated luminescence (OSL) intensity versus dose response of indigenously developed LiMgPO4:Tb,B (LMP) disks is linear in the range of 1 mGy–1 kGy. Currently, no other synthetic OSL phosphor is available, which covers such a large dose range. In order to assess the feasibility of using the phosphor in low‐dose food irradiation dosimetry (up to 1 kGy), dosimetric characterization of LMP‐based OSL dosimeter was carried out under both, gamma and electron beam irradiation. The doses estimated by LMP and routine dosimeters match well in the field trials. Hence, this phosphor has the potential to be used in phytosanitary application using radiation, where delivered doses are of the order of 0.01–1 kGy. Practical applications Food irradiation dosimetry, in India, is being carried out using chemical dosimeters such as Fricke, Ceric‐cerous sulphate, and Alanine‐electron paramagnetic resonance. The former two are liquid dosimeters kept in glass tubes and therefore need to be handled delicately during irradiation. The complex chemical preparation, sensitive to environmental conditions (temperature, humidity, etc.) and temperature changes, sensitive to UV radiation and the high sensitivity to impurities make these dosimetry systems inconvenient for routine applications. The OSL intensity versus dose response of indigenously developed LiMgPO4:Tb,B (LMP) has been observed to be linear up to 1 kGy. Apart from good dosimetric qualities, other qualities of the dosimeter system are quick readout, ease of handling, automated readout mechanisms, and integrity in harsh environments. The above‐discussed attributes make LMP‐based OSL dosimeter a potential candidate to carry out dosimetry during phytosanitary application of radiation in low‐dose range (0.01–1 kGy). This range includes irradiation of mangoes, onions, potatoes, etc.

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Section: Resultsmentioning

confidence: 99%

Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation

Menon

Singh

Kadam

et al. 2019

J Food Process Preserv

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Fullerenol C60(OH)36 protects human erythrocyte membrane against high-energy electrons

Grebowski

Kazmierska

Litwinienko

et al. 2018

Biochimica et Biophysica Acta (BBA) - Biomembranes

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Fullerenols (polyhydroxylated fullerene C) are nanomaterial with potentially broad applicability in biomedical sciences with high antioxidant ability, thus, we investigated the radioprotecting potential of fullerenol C(OH) on human erythrocytes irradiated by high-energy electrons of 6 MeV. The results demonstrate that C(OH) at concentration of 150 μg/mL protects the erythrocytes against the radiation-induced hemolysis (comparing to non-protected cells, we observed 30% and 39% protection for 0.65 and 1.3 kGy irradiation doses, respectively). The protecting effect was confirmed by 32% decreased release of potassium cations comparing to the cells irradiated without C(OH). Measurements of the amount of lactate dehydrogenase (LDH) released from the irradiated erythrocytes showed that the size of the pores formed by irradiation was not sufficient to release LDH across the erythrocyte membranes. We also report a significant decrease of the affinity of acetylcholinesterase (AChE) for the substrate in the presence of fullerenol, indicating the relatively strong adsorption of C(OH) to components of plasma membrane. Changes in membrane fluidity detected by fluorescence spectroscopy and conformational changes in membrane proteins detected by spin labeling suggest the dose-dependent formation of disulfide groups as an effect of oxidation and this process was inhibited by C(OH) We suppose that scavenging the ROS as well as adsorption of fullerenol to membrane proteins and steric protection of -SH groups against oxidation are responsible for the observed effects.

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Comparative Effects of Gamma-rays and Electron Beams on Peroxide Formation in Phosphatidylcholine

Cited by 2 publications

References 4 publications

Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation

Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation

Fullerenol C60(OH)36 protects human erythrocyte membrane against high-energy electrons

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Comparative Effects of Gamma-rays and Electron Beams on Peroxide Formation in Phosphatidylcholine

Cited by 2 publications

References 4 publications

Dosimetric characterization of LiMgPO4:Tb,B phosphor for its application in food irradiation

Dosimetric characterization of LiMgPO4:Tb,B phosphor for its application in food irradiation

Fullerenol C60(OH)36 protects human erythrocyte membrane against high-energy electrons

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Product

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Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation

Dosimetric characterization of LiMgPO₄:Tb,B phosphor for its application in food irradiation