Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis

Martínez‐Vizcaíno, Vicente; Cavero‐Redondo, Iván; Reina‐Gutiérrez, Sara; Gracia‐Marco, Luis; Gil-Cosano, José J.; Bizzozero-Peroni, Bruno; Rodríguez‐Artalejo, Fernando; Ubago‐Guisado, Esther

doi:10.1016/j.jshs.2023.01.002

Cited by 10 publications

(6 citation statements)

References 118 publications

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“…CE and AE are more conducive to the recovery of body functions. However, among previous studies on the effects of different PA types on HRQoL in all cancers, only some campaigns showed significant efficacy, possibly because of cancer type specificity [ 17 ]. Thus, the vast majority of physical activities significantly improved quality of life in BCS, which echoes previous findings on the potential protective effect of PA on BC risk in postmenopausal women [ 45 ].…”

Section: Discussionmentioning

confidence: 99%

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Comparative effects of different types of physical activity on health-related quality of life in breast cancer survivors: A systematic review, network meta-analysis, and meta-regression

Nie,

Yang,

Nie

et al. 2024

Heliyon

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Section: Discussionmentioning

confidence: 99%

“…In addition, this study did not specifically analyze BC patients but rather considered all cancer patients as a whole. Therefore, these results do not provide accurate guidance for BC patients when choosing PA [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Comparative effects of different types of physical activity on health-related quality of life in breast cancer survivors: A systematic review, network meta-analysis, and meta-regression

Nie,

Yang,

Nie

et al. 2024

Heliyon

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“… 46 Studies on the impact of exercise type on HRQoL in various adult and pediatric populations have varied in their conclusions, with some holding that exercise participation matters more than what type of exercise, 42 , 47 and others suggesting only certain types of exercise mediate a benefit to HRQoL. 48 , 49 It is yet to be established which may be true for children with chronic cardiac conditions like HCM. 50 Nonetheless, other studies in healthy children have associated increased physical activity with physical dimensions of HRQoL.…”

Section: Discussionmentioning

confidence: 99%

Exploring Health‐Related Quality of Life in Children With Hypertrophic Cardiomyopathy and Relationship to Physical Activity

Wagner,

Jeewa,

Pidborochynski

et al. 2024

JAHA

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Background Hypertrophic cardiomyopathy is a burdensome condition that inflicts both physical and psychological impairment on those with the disease, negatively impacting health‐related quality of life (HRQoL). Given the abundance of evidence suggesting a role of physical activity (PA) in modulating HRQoL in healthy populations of children, we sought to determine the relationship between HRQoL and PA in children diagnosed with hypertrophic cardiomyopathy. Methods and Results A multicenter prospective observational cohort study was conducted, with patients with hypertrophic cardiomyopathy aged 10 to 19 years being provided a wrist‐worn activity tracker (Fitbit Charge HR) to wear for 14 days. Patients self‐reported on Pediatric Quality of Life 4.0 quality of life inventory items, which were associated with PA metrics following covariate adjustment using linear regression. A total of 56 participants were recruited to the study. The median age at enrollment was 15.5 years (interquartile range, 13.8–16.8), and 16 out of 56 (29%) of the cohort were girls. The cohort reported decreased metrics of physical, psychosocial, and total summary scores compared with health reference populations, with scores comparable with that of published populations with chronic disease. Increased physical HRQoL scores were significantly associated with increased daily steps taken, distance traveled, and flights of stairs climbed. Conclusions These results show that impaired PA correlates with reduced HRQoL in children with hypertrophic cardiomyopathy, suggesting PA may partially mediate HRQoL in this population.

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“…Previous studies have reported beneficial effects of exercise training in mitigating QoL decline in BC patients during chemotherapy, but several have not found significant differences from control groups (14,35–38). Interestingly, in a recent meta-analysis, combined exercise training during cancer treatment was shown to provide greater benefits than only aerobic or resistance training (39). This may possibly explain, at least in part, the discrepancies in results between this RCT and previous studies that employed single modality exercise programs (14,37,38).…”

Section: Discussionmentioning

confidence: 99%

Exercise Training Benefits Health-Related Quality of Life and Functional Capacity during Breast Cancer Chemotherapy: A Randomized Controlled Trial

ANTUNES,

JOAQUIM,

SAMPAIO

et al. 2023

Medicine &Amp; Science in Sports &Amp; Exercise

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Purpose To examine the effectiveness of a supervised exercise training program (SETP) on health-related quality of life (HRQoL) and functional capacity in women with breast cancer (BC) undergoing chemotherapy. Methods Ninety-three women with early-stage BC were randomly allocated to a SETP plus usual care (Exercise, n = 47) or usual care alone (UC, n = 46). The SETP included 3 sessions per week, combining aerobic and resistance training, conducted concurrently over the chemotherapy. The EORTC Cancer Quality-of-Life-Questionnaire-Core-30 (QLQ-C30) and the BC-specific module (QLQ-BR23) were used to assess HRQoL. Functional capacity was analyzed by maximum voluntary handgrip strength (MVHS) and by the 30-second chair sit-to-stand test (30-s CST). These endpoints were assessed at baseline (t0); middle (t1; after 8 or 12 weeks of t0); and at the end of chemotherapy (t2; after 20 weeks of t0). Mean changes from baseline were assessed by an intention-to-treat approach. Results Mixed linear model analyses showed that Exercise group experienced less deterioration in several domains of QLQ-C30 at t2, including in global health status/QoL (Δ = 9.39 units; p = 0.034), QLQ-C30 summary score (Δ = 8.08 units; p < 0.001), physical (Δ = 15.14 units; p < 0.001), role (Δ = 21.81 units; p < 0.001), cognitive (Δ = 9.16 units; p = 0.032) and social functioning (Δ = 11.67 units; p = 0.038), compared to the UC group. Similarly, Exercise group exhibited significant lower levels of fatigue (Δ = -20.19 units; p < 0.001) and appetite loss (Δ = -13.69 units; p = 0.034), compared to the UC group. Significant between-group differences were observed on MVHS of the tumor/surgery upper limb side (Δ = 2.64 kg; p < 0.001) and contralateral limb (Δ = 2.22 kg; p < 0.001), and on the 30-s CST score (Δ = 3.56repetitions; p < 0.001), favoring the Exercise group. No differences were observed on QLQ-BR23 domains. Conclusions Exercise training was an effective complementary therapy to prevent the deterioration of HRQoL and functional capacity during chemotherapy in women with early-stage BC.

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Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis

Cited by 10 publications

References 118 publications

Comparative effects of different types of physical activity on health-related quality of life in breast cancer survivors: A systematic review, network meta-analysis, and meta-regression

Comparative effects of different types of physical activity on health-related quality of life in breast cancer survivors: A systematic review, network meta-analysis, and meta-regression

Exploring Health‐Related Quality of Life in Children With Hypertrophic Cardiomyopathy and Relationship to Physical Activity

Exercise Training Benefits Health-Related Quality of Life and Functional Capacity during Breast Cancer Chemotherapy: A Randomized Controlled Trial

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