“…It has been reported that CHX may also interfere with the taste function. Another objectionable feature of the antimicrobial is a very bitter taste and CHX can enhance calculus formation . Although tooth surface discoloration with CHX products may be an unwelcome side effect, lack of tooth surface discoloration with CHX products would suggest lack of clinical activity as is commonly stated ‘If it does not stain it does not work’ .…”
Within the limitations of this analysis, it may be concluded that toothbrushing with a CHX gel does not provide conclusive evidence. Brushing with a CHX dentifrice can be effective with regard to the control of plaque and gingivitis. Tooth surface discoloration was observed as side effect, which potentially can have a negative impact on patients' compliance.
“…It has been reported that CHX may also interfere with the taste function. Another objectionable feature of the antimicrobial is a very bitter taste and CHX can enhance calculus formation . Although tooth surface discoloration with CHX products may be an unwelcome side effect, lack of tooth surface discoloration with CHX products would suggest lack of clinical activity as is commonly stated ‘If it does not stain it does not work’ .…”
Within the limitations of this analysis, it may be concluded that toothbrushing with a CHX gel does not provide conclusive evidence. Brushing with a CHX dentifrice can be effective with regard to the control of plaque and gingivitis. Tooth surface discoloration was observed as side effect, which potentially can have a negative impact on patients' compliance.
“…[49][50][51][52] • Listerine mouthrinse has been reported to significantly reduce gingivitis and plaque in several additional human studies, [53][54][55] and to be less efficacious than Peridex ® (chlorhexidine) against plaque, [56][57][58] but less likely than Peridex to cause stains or supragingival calculus. 59 A 2001 human trial conducted by Pfizer (the manufacturer of Listerine) reported Listerine mouthrinse plus a fluoride toothpaste to be superior to Colgate Total dentrifice (toothpaste) for the reduction of plaque and gingivitis in 316 individuals with plaque after six months. 60 • There is early evidence that Listerine is able to penetrate dental plaque biofilm and kill gram-positive organisms interproximally (in the area most associated with periodontitis and dental caries, heretofore thought to be cleansed primarily only via flossing).…”
“…Essential oils (EOs) have shown evidence of efficacy and safety in gingivitis and supragingival plaque control (Overholser et al 1990, Sharma et al 2004, Stoeken et al 2007. EOs have the capacity to rupture the cell wall of certain microorganisms and inhibit their enzymatic activity (Kubert et al 1993).…”
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