Comparative Effectiveness of Treatment Modalities for Complex Aortic Aneurysms: A Network Meta-Analysis of Observational Studies

Zhou, Yang; Wang, Junwei; He, Hao; Li, Quanming; Li, Ming; Li, Xin; Shu, Chang

doi:10.1016/j.avsg.2023.02.023

Cited by 2 publications

(4 citation statements)

References 45 publications

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“…This level of accuracy is attained by incorporating direct comparison evidence with information from two treatments derived from a common comparator in indirect comparisons. [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

“…The discrepancy in long-term survival could be attributed to the use of the network meta-analysis. Direct and indirect comparisons offer greater accuracy when estimating outcomes, in comparison to pairwise comparisons [31][32][33].…”

Section: Reoperationmentioning

confidence: 99%

“…Network meta-analysis (NMA), which applies adjusted [31,32] and unadjusted [33] indirect comparison among treatments, offers a valuable approach to minimize heterogeneity and allocation biases, especially when analyzing both randomized controlled trials (RCTs) and observational studies. This technique has proved useful in attaining unbiased ndings [31][32][33]. To date, there has been no network meta-analysis comparing the treatment strategies of SPM-r, RMA, and MV-rpl with and without CABG for SIMR surgery, even though we only have evidence reported in pairwise meta-analysis [34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Best treatment option for secondary mitral regurgitation surgery: a network meta-analysis of randomized and non-randomized controlled studies.

Nappi,

Salsano,

Dimagli

et al. 2023

Preprint

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This study aims to determine whether subvalvular papillary muscle (PMs) repair (SPM-r) plus restrictive mitral valve (MV) annuloplasty (RMA) is the most effective treatment for patients with secondary ischemic mitral regurgitation. A network meta-analysis was conducted to investigate outcomes of randomized controlled trials, propensity-matched studies, and observational studies, comparing various treatments for secondary ischemic mitral regurgitation. The average follow-up duration for late mortality was 4.4 years. CABG without mitral valve surgery had a late mortality incidence of 3.7%. RMA demonstrated a rate of 6.5%, while RMA + CABG resulted in a rate of 4.1%. SPM-r plus RMA ± CABG and MV-rpl + CABG had rates of 4.4% and 5.1%. SUCRA analysis showed that coronary artery bypass grafting (CABG) was the most effective treatment for reducing late mortality (70.0%). This was followed by SPM-r plus RMA with or without CABG (62.4%). The top strategy for decreasing early death, reoperation, and readmission to the hospital for heart failure is SPM-r plus RMA with or without CABG, based on SUCRA probabilities (84.6%, 85.54%, and 86.3%, respectively). SPM-s plus RMA ± CABG has potential to reduce the risks associated with early mortality, reoperation, and re-hospitalization for heart failure. However, further research is required to substantiate these findings.

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“…This level of accuracy is attained by incorporating direct comparison evidence with information from two treatments derived from a common comparator in indirect comparisons. [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Section: Reoperationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Best treatment option for secondary mitral regurgitation surgery: a network meta-analysis of randomized and non-randomized controlled studies.

Nappi,

Salsano,

Dimagli

et al. 2023

Preprint

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Complex abdominal aortic aneurysms: a review of radiological and clinical assessment, endovascular interventions, and current evidence of management outcomes

Agarwal,

Hamady

2023

BJR|Open

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Endovascular aortic aneurysm repair is an established approach to treat abdominal aortic aneurysms, however, challenges arise when the aneurysm involves visceral branches with insufficient normal segment of the aorta to provide aneurysm seal without excluding those vessels. To overcome this, a range of technological developments and solutions have been proposed including fenestrated, branched, physician-modified stents, and chimney techniques. Understanding the current available evidence for each option is essential to select the most suitable procedure for each patient. Overall, the evidence for fenestrated endovascular repair is the most comprehensive of these techniques and shows an early post-operative advantage over open surgical repair but with a catch-up mortality in the mid-term period. In this review, we will describe these endovascular options, pre- and post-procedure radiological assessment and current evidence of outcomes.

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Comparative Effectiveness of Treatment Modalities for Complex Aortic Aneurysms: A Network Meta-Analysis of Observational Studies

Cited by 2 publications

References 45 publications

Best treatment option for secondary mitral regurgitation surgery: a network meta-analysis of randomized and non-randomized controlled studies.

Best treatment option for secondary mitral regurgitation surgery: a network meta-analysis of randomized and non-randomized controlled studies.

Complex abdominal aortic aneurysms: a review of radiological and clinical assessment, endovascular interventions, and current evidence of management outcomes

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