Comparative Effectiveness of the Bivalent (Original/Omicron BA.4/BA.5) mRNA COVID-19 Vaccines mRNA-1273.222 and BNT162b2 Bivalent in Adults With Underlying Medical Conditions in the United States
Hagit Kopel,
Van Hung Nguyen,
Alina Bogdanov
et al.
Abstract:This retrospective cohort study evaluated the relative vaccine effectiveness (rVE) of two bivalent (Original/Omicron BA.4/BA.5) vaccines mRNA-1273.222 versus BNT162b2 Bivalent in preventing COVID-19-related outcomes in adults with underlying medical conditions associated with increased risk for severe COVID-19.In a linked EHR-claims dataset, US adults (≥18 years) with ≥1 underlying medical condition of interest who received either bivalent vaccine between August 31, 2022, and February 28, 2023, were identified… Show more
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