Comparative effectiveness of herbal and conventional toothpaste on prevention of dental caries: systematic review and meta-analysis

Kengadaran, Shivashankar; Anusha, Divvi; Baskar, Kavya; Muthukrishnan, Kavitha; Pooraninagalakshmi, J; Prabakar, Jayashri

doi:10.4103/ijdr.ijdr_404_21

Cited by 2 publications

(1 citation statement)

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“…Dental caries is considered as the most common bacterial illness in children and affects 72% and 84% children aged 5-7 years and 12-15 years, respectively [1]. Antimicrobial products are increasingly being used as an adjuvant for mechanical plaque control to remove biofilm, thereby preventing dental caries [2].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial effects of dentifrices against Streptococcus mutans in children: a comparative in vitro study

2024

JOCPD

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Fluoridated dentifrices have antibacterial effects on children's teeth. On the other hand, the side effects encountered with the use of them have led researchers to look for safe alternatives. This study aimed to determine the antibacterial effect of different commercially available fluoride-free dentifrices on Streptococcus mutans (S. mutans) in comparison with different concentrations of fluoridated dentifrices. Study groups comprised of fluoride-free dentifrices, which contain Probiotic (Activated Charcoal Probiotic Dentifrice-Group P), Aloe Vera-Group AV and Salivary Proteins-Group SP. Fluoridated dentifrices containing 1450 ppm fluoride-Control Group 1 and 500 ppm fluoride-Control Group 2 served as control groups. Antibacterial activity was assessed by Minimum Inhibitory Concentrations and agar well diffusion assays on S. mutans. Biofilm inhibition assay was performed with dentifrices, which had antibacterial activities, and a negative control phosphate-buffered saline (Group PBS) on sterile hydroxyapatite discs against S. mutans. Statistical evaluation was performed. Only group AV showed an antibacterial effect on S. mutans, while control groups showed a similar antibacterial effect. The mean number of viable bacteria present in S. mutans biofilm in Control Group 1 and 2 and Group AV were statistically significantly lower than that in Group PBS, but there were no statistically significant differences between Control Groups and Group AV. Antibacterial activity of commercial dentifrices against S. mutans may be exerted by antibacterial components other than fluoride. Aloe veracontaining toothpaste showed an antibacterial effect on S. mutans, although not as much as the fluoride-containing toothpastes in the control groups. However, further in vivo and long-term studies are required.

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Section: Introductionmentioning

confidence: 99%