Comparative Effectiveness of Baloxavir Marboxil and Oseltamivir Treatment in Reducing Household Transmission of Influenza: A Post Hoc Analysis of the BLOCKSTONE Trial
Hideyuki Ikematsu,
Takamichi Baba,
Masaya M. Saito
et al.
Abstract:BackgroundThe transmission of influenza virus in households, especially by children, is a major route of infection. Prior studies suggest that timely antiviral treatment of ill cases may reduce infection in household contacts. The aim of the study was to compare the effects of oseltamivir (OTV) and baloxavir marboxil (BXM) treatment of index cases on the secondary attack rate (SAR) of influenza within household.MethodsA post hoc analysis was done in BLOCKSTONE trial—a placebo‐controlled, double‐blinded post‐ex… Show more
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