1990
DOI: 10.1097/00132586-199012000-00027
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Comparative Clinical Study of Induction and Emergence Time in Sevoflurane and Enflurane Anesthesia

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“…The blood-gas partition coefficient of sevoflurane is one-half to one-third that of isoflurane (0.69 vs 1.38). [3][4][5] This lower coefficient should result in a more rapid increase in alveolar drug concentration during induction of anesthesia, resulting in faster onset of effect than isoflurane. I t also will provide a more rapid change i n depth of anesthesia a n d faster decrease in alveolar concentration on termination, thus ensuring more rapid awakening than with isoflurane.…”
mentioning
confidence: 99%
“…The blood-gas partition coefficient of sevoflurane is one-half to one-third that of isoflurane (0.69 vs 1.38). [3][4][5] This lower coefficient should result in a more rapid increase in alveolar drug concentration during induction of anesthesia, resulting in faster onset of effect than isoflurane. I t also will provide a more rapid change i n depth of anesthesia a n d faster decrease in alveolar concentration on termination, thus ensuring more rapid awakening than with isoflurane.…”
mentioning
confidence: 99%