Comparative Changes in Sexual Dysfunction of Married Women after Colpoperineorrhaphy Versus Colpoperineorrhaphy with Additional Platelet Rich Plasma Injection

Al-Hamadani, Inas Taha; Shehab, Elaf mahmod; Aziz, Noor A.B.

doi:10.5958/0973-9130.2019.00309.8

Cited by 4 publications

(3 citation statements)

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“…Medical interviews were chosen as a method to diagnose or evaluate VL in 19 studies, which involved 4,409 subjects ( Table 3 ). 5 45 46 47 48 53 54 55 56 57 58 59 60 61 62 63 64 65 66 Eleven studies made a diagnosis effort of VL using interviews only. 46 47 53 54 55 57 58 59 60 61 63 Four studies chose interviews in combination with other measurement options, 48 56 62 65 and one study added the VL degree of bother evaluation.…”

Section: Resultsmentioning

confidence: 99%

“…Medical interviews were chosen as a method to diagnose or evaluate VL in 19 studies, which involved 4,409 subjects (Table 3). [5,[45][46][47][48][53][54][55][56][57][58][59][60][61][62][63][64][65][66] Eleven studies made a diagnosis effort of VL using interviews only [46,47,[53][54][55][57][58][59][60][61]63] Four studies chose interviews in combination with other measurement options, [48,56,62,65] and one study added the VL degree of bother evaluation. [5] Four studies reported treatment evaluation by conducting interviews.…”

Section: Medical Interviewsmentioning

confidence: 99%

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Current Perspectives in Vaginal Laxity Measurement: A Scoping Review

Aulia

Valeria

2023

Arch Plast Surg

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This scoping review aimed to identify and categorize the available measurement options for vaginal laxity (VL) their indications of use, and whether these measurements can sufficiently provide objective clinical judgment for cases indicated for vaginal rejuvenation with many treatment options nowadays. Systematic searches were conducted on five electronic databases, manually searching articles’ bibliographies and predetermined key journals with no date or study design limitations. We included all studies involving VL in their inclusion criteria, treatment indications, and outcome parameters. We used the Arksey and O’Malley frameworks as the guideline in writing this scoping review. Of the 9,464 articles identified, 66 articles and 11,258 subjects were included in the final analysis. The majority of studies were conducted in obstetrics and gynecology (73%), followed by plastic surgery (10%), medical rehabilitation (4.5%), dermatology (4.5%), and others (8%). Most studies originated from the North American region (30%). The following measurement tools were used: (1) interviews, (2) questionnaires, (3) physical/digital examinations, (4) perineometers, and (5) others. Our results suggested that subjective perception of laxity confirmed by directed interview or questionnaire is sufficient to confirm VL. Additional evaluation of PFM through digital examination or perineometer or other preferred tools and evaluation of sexual function through validated questionnaire (FSFI, FSDS-R, etc) should follow to ensure holistic care to patients. Future research on the psychometric properties (reliability and validity) of commonly used measurements and the correlation in between subjective and objective measurements should be initiated before their clinical applications.

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Section: Resultsmentioning

confidence: 99%

Section: Medical Interviewsmentioning

confidence: 99%

Current Perspectives in Vaginal Laxity Measurement: A Scoping Review

Aulia

Valeria

2023

Arch Plast Surg

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“…Supplement Data S1: PubMed search syntax and search string; Supplement Data S2: Reference list of all excluded studies with reasons for exclusion; Supplement Data S3: Risk of bias of RCTs; Supplement Data S4: Risk of bias in non-RCTs. References [13,47,[57][58][59][60][61][62][63][64][65][66][67][68][69][70] are cited in the supplementary materials.…”

Section: Supplementary Materialsmentioning

confidence: 99%

Efficacy and Safety of Platelet-Rich Plasma Injections for the Treatment of Female Sexual Dysfunction and Stress Urinary Incontinence: A Systematic Review

Dankova,

Pyrgidis,

Tishukov

et al. 2023

Biomedicines

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Introduction: There is no clear evidence in the literature that platelet-rich plasma (PRP) injections improve female sexual dysfunction (FSD) and female stress urinary incontinence (SUI). Objectives: A systematic review was performed to study the efficacy and safety of PRP injections in women with the above pathologies, as well as to explore the optimal dosing, frequency and area of injections, and duration of treatment. Methods: A systematic search on PubMed, Embase and the Cochrane Library database was performed, as well as sources of grey literature from the date of database or source creation to January 2023. After title/abstract and full-text screening, clinical studies on humans evaluating the efficacy of PRP in gynecological disorders using standardized tools were included. Risk of bias was undertaken with RoB-2 for randomized-controlled trials (RCT) and the Newcastle-Ottawa Scale (NOS) for observational studies. Results: Four prospective and one retrospective study explored FSD, while six prospective and one RCT evaluated female SUI. A total of 327 women with a mean age of 51 ± 12 years were included. For FSD, PRP significantly improved the Female Sexual Function Index (FSFI), the Vaginal Health Index (VHI) and the Female Sexual Distress score (FSDS). For SUI, PRP led to a significant improvement in the International Consultation on Incontinence Questionnaire—Short Form (ICIQ-SF) and the Urogenital Distress Inventory (UDI-6). The identified RCT reported a significantly higher mean score of ICIQ-SF (p < 0.05) and UDI-6 (p < 0.01) in the midurethral sling group compared to the PRP injections group. Regarding the risk of bias, the RCT was characterized by high risk, whereas the observational studies were of moderate risk. The protocol for PRP injections for FSD is the injection of 2 mL of PRP into the distal anterior vaginal wall once a month for 3 months. For female SUI, 5–6 mL of PRP should be injected into the periurethral area once a month for 3 months. Conclusions: Despite the promising initial results of PRP injections, the level of current evidence is low due to methodological issues in the available studies. It becomes clear that there is an emerging need for high-quality research examining PRP injections for the treatment of FSD and female SUI.

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