Comparative bioavailability of vitamins in human foods sourced from animals and plants

Chungchunlam, Sylvia M.S.; Moughan, Paul J.

doi:10.1080/10408398.2023.2241541

Cited by 15 publications

(6 citation statements)

References 230 publications

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“…The absorption of VitK mainly occurs in the jejunum and ileum, and minimally in the colon; this process requires the presence of dietary fat and the action of pancreatic juices in the duodenum for solubilization within mixed micelles [ 55 ]. VK2 is easier to absorb and has a longer half-life than VK1, which is particularly evident for long-chain menaquinones with high lipophilicity [ 56 ].…”

Section: Vitamin Kmentioning

confidence: 99%

Zinc, Magnesium and Vitamin K Supplementation in Vitamin D Deficiency: Pathophysiological Background and Implications for Clinical Practice

Bleizgys

2024

Nutrients

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Zinc, magnesium, and vitamin K are important nutrients for humans. There are various factors that contribute to the development of their deficiency, which might result in or exacerbate various diseases. These nutrients can also interact with vitamin D metabolism and activity. This review discusses the main aspects of zinc, magnesium and vitamin K metabolism and action in the body, their clinical significance, and the “crosstalk” with vitamin D, as well as providing general suggestions for clinical practice when supplementation with these nutrients might be useful, in addition to vitamin D supplementation.

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Section: Vitamin Kmentioning

confidence: 99%

Zinc, Magnesium and Vitamin K Supplementation in Vitamin D Deficiency: Pathophysiological Background and Implications for Clinical Practice

Bleizgys

2024

Nutrients

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“…Vitamins are vital components of enzyme systems that assist chemical reactions inside the body. They are necessary for the integrity of cell membranes, nerve and muscle function, bone formation, and overall good health [53]. Different species have varying dietary needs for vitamins, some being metabolic essentials while others can be synthesised from other food or metabolic constituents.…”

Section: Free Radicals and Non-radical Oxidants Examplesmentioning

confidence: 99%

“…Several factors influence vitamin requirements and utilisation, including physiological makeup and production function; confinement rearing without pasture; stress, disease, and adverse environmental conditions; vitamin antagonists; use of antimicrobial drugs; and body vitamin reserve [54,55]. This specific group of substances are differentiated from others by their organic nature, and their classification depends on chemical nature and function [53]. Thus, the classification of vitamins is divided into two main categories: water-soluble and fat-soluble vitamins.…”

Section: Free Radicals and Non-radical Oxidants Examplesmentioning

confidence: 99%

The Role of Vitamins in Mitigating the Effects of Various Stress Factors in Pigs Breeding

Smołucha,

Steg,

Oczkowicz

2024

Animals

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Good practices in farm animal care are crucial for upholding animal well-being, efficiency, and health. Pigs, like other farm animals, are exposed to various stressors, including environmental, nutritional, chemical, psychological, physiological, and metabolic stressors, which can disrupt their internal balance and compromise their well-being. Oxidative stress can adversely affect animal performance, fertility, and immunity, leading to economic losses for farmers. Dietary considerations are hugely important in attaining these objectives. This paper reviews studies investigating the impact of additional vitamin supplementation on stress reduction in pigs. Vitamin A can be beneficial in counteracting viral and parasitic threats. Vitamin B can be a potential solution for reproductive issues, but it might also be beneficial in reducing the effects of inappropriate nutrition. Vitamin C plays a vital role in reducing the effects of heat stress or exposure to toxins in pigs. Vitamin D proves to be beneficial in addressing stress induced mostly by infections and weaning, while vitamin E has been shown to mitigate the effects of toxins, heat stress, or transport stress. This review highlights the potential benefits of these dietary antioxidants in maintaining pig health, enhancing productivity, and counteracting the adverse effects of various stressors. Understanding the role of vitamins in pig nutrition and stress management is vital for optimising farm animal welfare and production efficiency.

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“…1 Discovered in 1933, its biologically active form, D-pantothenic acid (DPA), is vital for hair, skin, and blood health. 2 However, due to DPA's instability, it is primarily available commercially as calcium D-pantothenate in various industries including pharmaceuticals, food, feed processing, and cosmetics. 3 The biosynthetic method offers advantages such as mild processing, eco-friendliness, and costeffectiveness, paving the way for potential large-scale Dpantothenic acid production using biological means.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Pantothenic acid, or vitamin B5, is crucial for metabolic functions in organisms . Discovered in 1933, its biologically active form, d -pantothenic acid (DPA), is vital for hair, skin, and blood health . However, due to DPA’s instability, it is primarily available commercially as calcium d -pantothenate in various industries including pharmaceuticals, food, feed processing, and cosmetics .…”

Section: Introductionmentioning

confidence: 99%

Enhancing the Thermal Stability and Enzyme Activity of Ketopantoate Hydroxymethyltransferase through Interface Modification Engineering

Cai,

Shi,

Wang

et al. 2024

J. Agric. Food Chem.

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Ketopantoate hydroxymethyltransferase (KPHMT) plays a pivotal role in D-pantothenic acid biosynthesis. Most KPHMTs are homodecamers with low thermal stability, posing challenges for protein engineering and limiting output enhancement. Previously, a high-enzyme activity KPHMT mutant (K25A/E189S) from Corynebacterium glutamicum was screened as mother strain (M0). Building upon this strain, our study focused on interface engineering modifications, employing a multifaceted approach including integrating folding-free energy calculation, B-factor analysis, and conserved site analysis. Preliminary screening led to the selection of five mutants in the interface�E106S, E98T, E98N, S247I, and S247D�showing improved thermal stability, culminating in the double-site mutant M8 (M0-E98N/S247D). M8 exhibited a T 1/2 value of 288.79 min at 50 °C, showing a 3.29fold increase compared to M0. Meanwhile, the T m value of M8 was elevated from 53.2 to 59.6 °C. Investigations of structural and molecular dynamics simulations revealed alterations in surface electrostatic charge distribution and the formation of increased hydrogen bonds between subunits, contributing to enhanced thermal stability. This investigation corroborates the efficacy of interface engineering modifications in bolstering KPHMT stability while showing its potential for positively impacting industrial Dpantothenic acid synthesis.

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Comparative bioavailability of vitamins in human foods sourced from animals and plants

Cited by 15 publications

References 230 publications

Zinc, Magnesium and Vitamin K Supplementation in Vitamin D Deficiency: Pathophysiological Background and Implications for Clinical Practice

Zinc, Magnesium and Vitamin K Supplementation in Vitamin D Deficiency: Pathophysiological Background and Implications for Clinical Practice

The Role of Vitamins in Mitigating the Effects of Various Stress Factors in Pigs Breeding

Enhancing the Thermal Stability and Enzyme Activity of Ketopantoate Hydroxymethyltransferase through Interface Modification Engineering

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