Comparative Bio-Potential Effects of Fresh and Boiled Mountain Vegetable (Fern) Extract Mediated Silver Nanoparticles

Abstract

This current investigation was designed to synthesize Ag nanoparticles (AgNPs) using both the fresh (Fbf) and boiled (Bbf) Korean mountain vegetable fern (named Gosari) extracts and make a comparative evaluation of its multi-therapeutic potentials. The screening of phytochemicals in the fern extract was undertaken. The synthesized fern-mediated silver nanoparticles are characterized and investigated for their bio-potential like α-glucosidase inhibition, antioxidant, and cytotoxicity prospects. The obtained AgNPs were characterized by the UV-Vis Spectra, SEM, EDS, XRD, FTIR, DLS, Zeta potential analysis, etc. The synthesis of the Fbf-AgNPs was very fast and started within 1 h of the reaction whereas the synthesis of the Bbf-AgNPs synthesis was slow and it started around 18 h of incubation. The UV-Vis spectra displayed the absorption maxima of 424 nm for Fbf-AgNPs and in the case of Bbf-AgNPs, it was shown at 436 nm. The current research results demonstrated that both Fbf-AgNPs and Bbf-AgNPs displayed a strong α-glucosidase inhibition effect with more than 96% effect at 1 µg/mL concentration, but the Bbf-AgNPs displayed a slightly higher effect with IC50 value slightly lower than the Fbf-AgNPs. Both Fbf-AgNPs and Bbf-AgNPs displayed good antioxidant effects concerning the in vitro antioxidant assays. In the case of the cytotoxicity potential assay also, among both the investigated Fbf-AgNPs and Bbf-AgNPs nanoparticles, the Bbf-AgNPs showed stronger effects with lower IC50 value as compared to the Fbf-AgNPs. In conclusion, both the fern-mediated AgNPs displayed promising multi-therapeutic potential and could be beneficial in the cosmetics and pharmaceutical sectors. Though the synthesis process is rapid in Fbf-AgNPs, but it is concluded from the results of all the tested bio-potential assays, Bbf-AgNPs is slightly better than Fbf-AgNPs.

Biogenic Synthesis, Characterization, and In Vitro Biological Evaluation of Silver Nanoparticles Using Cleome brachycarpa

“…CB -AgNPs showed momentous DPPH scavenging activity compared to CB -extract ( Figure 8 ) because of their high secondary metabolites (flavonoids, phenolic, terpenoids, and alkaloids) [ 29 ]. It was observed that with the increase in concentration, the antioxidant activity of CB -AgNPs increased ( Figure 9 a), which was comparable with and in agreement with previous findings [ 54 , 55 ].…”

Biosynthesis and Characterization of Silver Nanoparticles Using Tribulus terrestris Seeds: Revealed Promising Antidiabetic Potentials

“…[ 2 ], and the development of diagnostic and therapeutic materials and devices [ 3 ]. Metal nanoparticles can be produced using a variety of techniques, such as chemical reduction, microwave and UV radiation, photochemistry, and sonoelectrochemistry [ 4 ]. However, the use of toxic chemicals in these methods has led to a need for alternative, eco-friendly, and straightforward synthetic methods that utilize the reducing properties of natural compounds.…”