“…PCV is often found in the extramacular area, whereas tAMD always exists within the macular area [7,8]. In addition, the natural course and response to treatment are often different between tAMD and PCV [9,10,11,12,13,14,15,16,17]. Moreover, recent genetic studies suggested a possible difference in the genetic background between tAMD and PCV [18,19,20,21,22,23,24,25], as well as the existence of heterogeneity among PCV cases [26,27].…”