Comparative Assessment of Efficacy of Tadalafil and Tamsulosin Alone and in Combination Among Men With Benign Prostatic Hyperplasia

Abstract

Background: Men in 5th and 6th decade of life experience a fall in the quality of life owing to Lower Urinary tract symptoms arising out of benign prostatic hypertrophy. The medical management protocol involves either monotherapy or combination. The present study was done to comparatively evaluate the efficacy of monotherapy as well as combination therapy in treatment of such patients using two drugs, namely Tadalafil and Tamsulosin. Methodology: The study comprised of 90 subjects divided equally in three groups. Group A and B were subjected to monotherapy using Tadalafil and Tamsulosin respectively, while Group C was provided a combination. Observations: There was statistically significant difference in subjects having Tamsulosin alone or in combination therapy as compared to subjects given Tadalafil alone. Conclusion: Tamsulosin alone or in combination therapy has shown a better outcome in the selected study subjects.
 Keywords: BPH, LUTS, Tamsulosin, Tadalafil