Comparative Assessment of Antimicrobial Efficacy of Different Antibiotic Coated Gutta-Percha Cones on Enterococcus faecalis An Invitro Study

Antibacterial Activity of Endodontic Gutta-Percha—A Systematic Review

“…Root canal therapy becomes necessary when the defense mechanisms of the vital dental pulp are compromised, leading to the removal of infected necrotic tissue [9,10]. The primary objective of endodontic treatment is to eliminate microbial pathogens and prevent reinfection of the canal [1][2][3][5][6][7][8][9][11][12][13][14][15][16][17]. Another important stage of endodontic treatment is root canal obturation, which aims to establish a hermetic seal in the endodontic structures, thereby maintaining the aseptic environment achieved during the earlier stages of root canal treatment [8].…”

“…Another important stage of endodontic treatment is root canal obturation, which aims to establish a hermetic seal in the endodontic structures, thereby maintaining the aseptic environment achieved during the earlier stages of root canal treatment [8]. Root canal therapy is a crucial measure for preserving teeth and avoiding their extraction [10,11,18]. Advancements in technology, a deeper understanding of root canal anatomy, and the use of improved biocompatible materials have collectively contributed to the increased success rate of root canal therapy [11].…”

“…Root canal therapy is a crucial measure for preserving teeth and avoiding their extraction [10,11,18]. Advancements in technology, a deeper understanding of root canal anatomy, and the use of improved biocompatible materials have collectively contributed to the increased success rate of root canal therapy [11]. Dental materials selected for root canal filling play a pivotal role in the success of endodontic treatments.…”

“…This radiographic clarity is instrumental in evaluating the adaptation and placement of obturation materials, ensuring a thorough and homogenous fill. These considerations collectively contribute to the overall quality of proper obturation, a critical factor in the long-term success of endodontic therapy [1,2,5,8,9,11]. Importantly, these materials should not induce irritation in periapical tissues [19] (see Figure 1).…”

“…Importantly, these materials should not induce irritation in periapical tissues [19] (see Figure 1). The failure of root canal therapy is typically attributed to reinfection of the root canal space after root canal obturation [3,4,9,11]. The intricate root canal anatomy, characterized by fins, isthmi, ramifications, and dentinal tubules, makes complete disinfection of the root canal system challenging, if not nearly impossible [20,21].…”