2021
DOI: 10.3390/genes12081148
|View full text |Cite
|
Sign up to set email alerts
|

Comparative Aspects of Annelid Regeneration: Towards Understanding the Mechanisms of Regeneration

Abstract: The question of why animals vary in their ability to regenerate remains one of the most intriguing questions in biology. Annelids are a large and diverse phylum, many members of which are capable of extensive regeneration such as regrowth of a complete head or tail and whole-body regeneration, even from few segments. On the other hand, some representatives of both of the two major annelid clades show very limited tissue regeneration and are completely incapable of segmental regeneration. Here we review experim… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
49
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 31 publications
(72 citation statements)
references
References 143 publications
(383 reference statements)
1
49
0
Order By: Relevance
“…Specifically, these posterior body fragments exhibit transformations in touch sensory fields, giant fiber conduction velocity, axonal diameter, and other physiological properties appropriate for the fragment’s new positional identity ( Drewes and Fourtner, 1990 ; Martinez et al, 2006 ). These dramatic changes within the original body fragments have been defined as morphallaxis ( Morgan, 1901 ; Berrill, 1952 ; Martinez Acosta and Zoran, 2015 ; Kostyuchenko and Kozin, 2020 ; Kostyuchenko and Kozin, 2021 ). Morphallaxis is a pattern of regeneration where existing tissues are transformed without the involvement of stem cell differentiation ( Holstein et al, 2003 ; Agata et al, 2007 ; Martinez Acosta and Zoran, 2015 ; Özpolat and Bely, 2016 ).…”
Section: The Present: Burning Topics In Lumbriculus Regeneration Researchmentioning
confidence: 99%
See 1 more Smart Citation
“…Specifically, these posterior body fragments exhibit transformations in touch sensory fields, giant fiber conduction velocity, axonal diameter, and other physiological properties appropriate for the fragment’s new positional identity ( Drewes and Fourtner, 1990 ; Martinez et al, 2006 ). These dramatic changes within the original body fragments have been defined as morphallaxis ( Morgan, 1901 ; Berrill, 1952 ; Martinez Acosta and Zoran, 2015 ; Kostyuchenko and Kozin, 2020 ; Kostyuchenko and Kozin, 2021 ). Morphallaxis is a pattern of regeneration where existing tissues are transformed without the involvement of stem cell differentiation ( Holstein et al, 2003 ; Agata et al, 2007 ; Martinez Acosta and Zoran, 2015 ; Özpolat and Bely, 2016 ).…”
Section: The Present: Burning Topics In Lumbriculus Regeneration Researchmentioning
confidence: 99%
“…Many annelid lineages show amazing abilities to regrow an entire new body from a single fragment, while others (sometimes closely related) find themselves incapable of regenerating heads, or even tails ( Zattara and Bely, 2016 ). Despite their foundational importance, many basic questions about the developmental mechanisms underlying annelid regeneration are still open, and only recently are being addressed using modern molecular approaches ( Özpolat and Bely, 2016 ; Zattara, 2020 ; Kostyuchenko and Kozin, 2021 ).…”
Section: Introductionmentioning
confidence: 99%
“…Together with piwi , vasa and some other genes, nanos is well known as a member of the germline multipotency program (GMP) genes and a strong molecular marker for the multipotent state of cells [ 12 ]. De novo expression of this gene, for example in the regenerative blastema, may indicate local cell dedifferentiation [ 11 , 13 , 14 , 15 , 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
“…This review summarizes data on posterior regeneration for the annelid Capitella teleta and outlines its advantages for future regeneration research. Annelid regeneration is briefly introduced here to provide context, and the reader is encouraged to look at one of the numerous excellent comprehensive reviews on various aspects of annelid regeneration [1][2][3][4][5][6][7][8][9].…”
Section: Introductionmentioning
confidence: 99%
“…More recent efforts have focused on beginning to build a molecular understanding of events such as wound response and cellular reprogramming during annelid regeneration. These studies have included spatial and temporal characterization of genes expressed at the wound site using both candidate gene approaches and generation of bulk transcriptome/RNA Seq datasets (reviewed in [9]). The role of molecular signaling in the regeneration response has been investigated using chemical inhibitors studies in a few cases; one such study implicates FGF signaling in the control of cell division in the regenerating tissue [16].…”
Section: Introductionmentioning
confidence: 99%