Comparative anthelmintic efficacy of ivermectin delivered through different routes in gastrointestinal nematode infected dogs

Abstract

Ivermectin is one of the most effective and widely used antiparasitic agents ever discovered because of its broad spectrum activity against nematodes and arthropods. Therefore, the study was conducted to determine the comparative anthelmintic efficacy of ivermectin by giving through oral and subcutaneous routes in clinically infected dogs and also to check the prevalence of gastrointestinal nematode in dogs in Bhubaneswar, Odisha. Total 154 dogs with clinical signs of gastroenteritis were examined for the presence of nematodal ova in their faecal sample and 64 were found positive (41.56 %). The screened dogs were divided in to two groups (n = 10 each), first group of animals were treated with ivermectin @ 0.5 mg/kg body weight by subcutaneous route and the second group with same dose of ivermectin through oral route. Efficacy of ivermectin was evaluated based on egg per gram (EPG), haematological and biochemical parameters. It is concluded that, Prevalence of gastrointestinal nematodes are high in dogs in the climatic condition of Bhubaneswar, Odisha. Ivermectin was found effective when administered through either of the routes. Haemato-biochemical parameters were restored after administration of ivermectin and also significant reduction in EPG was found in dogs treated with ivermectin by both the routes, but no significant difference was observed in EPG between oral and subcutaneous treated dogs in various intervals of study.

Prevalence of gastrointestinal and haemo-parasites in hunting dogs in Zaria, Nigeria

“…The distribution and intensity of the diseases are mainly influenced by geographical, climatic, cultural and economic factors (Robertson et al, 2000). The level of hygienic conditions, lack of Veterinary supervision and public awareness campaign concerning zoonotic diseases exacerbate the transmission of the diseases (Panigrahi et al, 2014). The aim of the study was to evaluate the prevalence of endoparasites in hunting dogs in Zaria, Kaduna State.…”

Evaluation of gastrointestinal helminths in canine population of Bhubaneswar, Odisha, India: a public health appraisal

“…Parasitic diseases account for important health hazard in human beings and animals around the globe including India [1]. India, as a tropical country, has a wide range of climatic zones, which make it vulnerable for a diverse range of parasites of medical and veterinary importance, whose transmission and geographical distribution are closely linked to regional temperature, rainfall and humidity.…”