Comparative androgenic, myotrophic and antigonadotrophic properties of some anabolic steroids

Effects of large doses of anabolic steroids.

“…In both patients, large doses of anabolic steroids have reduced the output of testosterone and gonadotrophins; similar effects have been noticed in rats (Boris et al, 1969). Some reversal of these effects has been seen in both patients on stopping treatment.…”

Anabolic steroids in athelics: crossover double-blind trial on weightlifters.

“…9 Objective evidence of improved athletic performance is sparse and contradictory. Androstenolone 20 mg/day in a doubleblind trial among a group of students of mixed athletic habits produced no significant improvements in performance,' 0 whereas methandienone 5 mg/day did produce improvement in a group of experienced weightlifters in a non-double-blind trial."'…”

Synthesis and antiproliferative activity of new D-homo and D-seco androstane derivatives

“…Postoje zna ajne razlike u aktivnosti jedinjenja, ak i kada su pore enja pravljena istom standardnom procedurom. 103,104 Relativna aktivnost jedinjenja je procenjena pomo u raznih tehnika, pa je stoga procena efekata strukturnih modifikacija na aktivnost komplikovanija za prou avanje reaktivnosti steroidnih jedinjenja u zavisnosti od strukture (SAR -structureactivity relationship). Strukturne karakteristike testosterona, koje uti u na ekspresiju androgene i/ili anaboli ke aktivnosti su prikazane na slici 2.…”