Comparative analysis of metabolic models of microbial communities reconstructed from automated tools and consensus approaches
Yunli Eric Hsieh,
Kshitij Tandon,
Heroen Verbruggen
et al.
Abstract:Genome-scale metabolic models (GEMs) of microbial communities offer valuable insights into the functional capabilities of their members and facilitate the exploration of microbial interactions. These models are generated using different automated reconstruction tools, each relying on different biochemical databases that may affect the conclusions drawn from the in silico analysis. One way to address this problem is to employ a consensus reconstruction method that combines the outcomes of different reconstructi… Show more
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