Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients

Hand-assisted laparoscopic partial nephrectomy after 60 cases: comparison with open partial nephrectomy

“…The OPN patient died of unrelated cardiac causes 7 months post ablation. Equivalent long-term oncological follow-up between laparoscopic and OPN has been shown by several studies [6,12]. Specifically, Permpongkosol et al reported that, for patients with T1N0M0 lesions, recurrence and survival rates were equivalent between laparoscopic and OPN (follow-up of 40.4 months laparoscopic, 49.7 months open).…”

“…Early studies comparing open and laparoscopic partial nephrectomy reported advantages of the laparoscopic approach including decreased postoperative pain, blood loss, hospital stay, and narcotic use [5][6][7]. These studies, however, reported some unfavorable outcomes associated with the laparoscopic approach, including increased operative time [7], lower renal function at 4 and 6 months [5], longer warm ischemia times, increased major intraoperative complications, and more postoperative urologic complications [6], tempering the enthusiasm for the laparoscopic approach.…”

“…These studies, however, reported some unfavorable outcomes associated with the laparoscopic approach, including increased operative time [7], lower renal function at 4 and 6 months [5], longer warm ischemia times, increased major intraoperative complications, and more postoperative urologic complications [6], tempering the enthusiasm for the laparoscopic approach. More recent comparisons have reported the advantages of laparoscopic partial nephrectomy with comparable oncological results for T1N0M0 renal cell carcinoma at 3-and 5-year follow-up [12,13].…”

“…While observation and ablative techniques are appropriate in some patients, partial nephrectomy is the surgical standard of care for favorably located, small kidney tumors. Traditionally, partial nephrectomy has been performed via open technique; however, minimally invasive approaches to the procedure have recently been shown to be less morbid than open methods [3][4][5][6][7].…”

Intraoperative fluid management in laparoscopic live-donor nephrectomy: Challenging the dogma

“…Although there are no long-term human studies of donor renal function following LLDN, animal studies suggest that there is little renal function impairment in rats 1 year after undergoing LLDN [9]. When comparing laparoscopic versus open partial nephrectomy for renal tumors, Gill et al did not find a difference in renal function up to 30 days postoperatively [6]. The creatinine rise is unlikely to be of clinical significance.…”