Comparative analysis of integrated diaphragmatic electromyography during three different modalities of mechanical ventilation (NAVA, PSV and PCV)

Mazzoleni, Stefano; Vagheggini, Guido; Ambrosino, Nicolino; Vlad, E. Panait; Carrozza, Maria Chiara

doi:10.1109/biorob.2012.6290857

Cited by 1 publication

(1 citation statement)

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“…A previous study on a different patients group showed similar changes from BL to FL [13] under both ventilation modes. These results should be confirmed by further studies on larger number of NMD patients due to the important clinical implications.…”

Section: Discussionsupporting

confidence: 52%

Diaphragmatic electromyography analysis during two different mechanical ventilation techniques in patients with neuromuscular diseases

Mazzoleni

Vagheggini²,

Buono

et al. 2014

5th IEEE RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics

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The aim of the present study is to analyse changes in the diaphragmatic electromyography integral, as a direct expression of the patients inspiratory effort and index of neural respiratory drive, and parameters associated with ventilatory function in patients with prolonged weaning under Pressure Support Ventilation (PSV) and Neurally Adjusted Ventilatoy Assist (NAVA). Five patients affected by neuromuscular diseases were recruited. Each patient underwent a sequence of decreasing inspiratory support levels under NAVA and PSV, randomly assigned, from a baseline to a final level. At baseline, the value of diaphragmatic electromyography integral was higher under NAVA compared to PSV and increased in both ventilation modes progressing to final level. Higher values of inspiratory time and neural inspiratory time were observed in PSV at final level compared to baseline level. Conversely, a significant decrease of neural inspiratory time from baseline level to final level was observed in NAVA. Tidal volume at final level was significantly lower than at baseline level in both ventilation modes. These preliminary results show that in prolonged weaning patients affected by neuromuscular disease NAVA ventilation is associated to a higher diaphragmatic electromyography activity compared to PSV with same level of ventilation and subjective comfort

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Section: Discussionsupporting

confidence: 52%