During the last decades, the plastic surgery ield has made important advances in terms of clinical results and developing new surgical techniques, minimizing complications and reducing the mortality rates. An innovative and new technique is called High Deinition LipoSculture. This is an advanced sculpting technique that creates an athletic and sculpted appearance. The aim of this chapter is to review the principal concepts that involve this technique and describe its clinical application. An electronic literature review was conducted in order to ind the most recent medical literature published in this ield. Keywords used were plastic surgery, liposuction, body contouring, aesthetic medicine, and surgical procedure. High deinition liposuction procedures should be considered revolutionary in the plastic surgery ield.