2016
DOI: 10.1590/s1679-45082016ao3484
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Comparative analysis of ampoules and vials in sterile and conventional packaging as to microbial load and sterility test

Abstract: Objective To compare sterility and microbial (bacteria and fungi) load in the outer part of hyperbaric bupivacaine (Neocaína®) in ampoule and bupivacaine in vial, in conventional and sterile pack formulations.Methods The sterile packs were divided into two groups: G1 (n=16) with ampoules and G2 (n=16) with vials. Conventional formulations were divided into two groups, being G3 (n=16) with ampoules and G4 (n=16) with vials. The ampoules and vials were opened and had their content drawn. The empty bottles were t… Show more

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Cited by 2 publications
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“…When sterility and microbial (bacteria and fungi) load on the outside of ampoules and vials of hyperbaric bupivacaine from conventional or sterile packaging were compared, the use of sterile packaging reduced the microbial load, and decreased the possibility of potential anesthetic solution contamination. 151 …”
Section: Safety In the Administration Of Drugsmentioning
confidence: 99%
See 1 more Smart Citation
“…When sterility and microbial (bacteria and fungi) load on the outside of ampoules and vials of hyperbaric bupivacaine from conventional or sterile packaging were compared, the use of sterile packaging reduced the microbial load, and decreased the possibility of potential anesthetic solution contamination. 151 …”
Section: Safety In the Administration Of Drugsmentioning
confidence: 99%
“… 149 , 150 Sterile packaging is recommended as a way of increasing safety and reducing bacterial contamination of the solutions used in regional anesthesia. 149 , 151 …”
Section: Safety In the Administration Of Drugsmentioning
confidence: 99%