Comparative analysis of a presbyopia-correcting intraocular lens that combines extended depth-of-focus and bifocal profiles with a standard monofocal intraocular lens

Abstract

Background Recently, a new presbyopia-correcting intraocular lens (IOL) that combines extended depth-of-focus and bifocal profiles (ZFR00: Tecnis® Synergy®, Johnson & Johnson Vision, Santa Ana, CA, USA) has been established and several studies have been reported. We attempted to compare the performance with a standard IOL (ZCB00: Tecnis® monofocal, Johnson & Johnson Vision, Santa Ana, CA, USA) manufactured using the same material from the same company, which has been extensively used worldwide. Methods The medical records of patients undergoing cataract surgery with ZCB00 or ZFR00 implantation between March 2021 and September 2021 and with available 3-month visit data were reviewed. Uncorrected near, intermediate, and distance visual acuity (VA), corrected distance VA, and optical quality were the main outcome measures. Results This study included forty-six patients (64 eyes), with twenty-one patients (32 eyes) implanted with ZCB00 and twenty-five patients (32 eyes) implanted with ZFR00. The average age of the patients was 66.0 ± 10.1 (range: 40 to 82) and 65.1 ± 4.7 (range: 59 to 77) years in the ZCB00 and ZFR00 groups, respectively. The preoperative characteristics did not differ significantly between the two groups. Compared to the ZCB00 group, the ZFR00 group demonstrated significantly superior intermediate and near VA (p < 0.001) at 3 months postoperatively. The ZFR00 group showed significantly lower objective measured optical quality than that in the ZCB00 group. Conclusions The ZFR00 exhibited a continuous range of vision and a smooth defocus curve, while the ZCB00 provided superior objective optical quality.

Clinical outcomes of a new four-haptic hydrophobic presbyopia-correcting intraocular lens

“…Not surprisingly, the objective optical quality of PL E, a standard monofocal IOL, was superior to Symbiose. This is a common finding in studies comparing monofocal IOL with presbyopia-correcting IOL 28 , 29 .…”

“…Similar to Symbiose, Tecnis Synergy (Johnson & Johnson Vision, Santa Ana, CA, USA) is a bifocal IOL combined with EDOF technology for a greater range of vision 29 . A comparison of the performance and characteristics of these two IOLs under the same conditions would be meaningful.…”

“…Additionally, the evaluation of objective optical quality with diffractive IOLs can be limited due to the light loss caused by the diffraction patterns 30 . The HD analyzer can account for this diffusion by measuring higher OSI values in the diffraction rings 29 . The study also found that the individuals in the Symbiose group were younger, which may have influenced the results due to the effect of age on pupil size.…”

Clinical Visual Outcomes Over a Range of Vision Following Cataract Surgery with Bilateral Implantation of a Hybrid Multifocal and Extended Depth of Focus Intraocular Lens

“…Several published studies have demonstrated that it performs well for distance, intermediate, and near vision at various ranges. [6][7][8][9][10][11][12][13] These studies have reported clinical outcomes from bilateral implantation of this lens in patients at near focal points of 33, 40, 66, and 80 cm. This author's experience with the Tecnis Symfony EDOF IOL (Johnson & Johson) 14 Institutional Review Board approval was obtained by the Houston Methodist Research Institute, Houston, TX.…”

Clinical performance after implantation of an EDOF intraocular lens in the dominant eye and a presbyopia-correcting intraocular lens in the nondominant eye

“…[11][12][13] Although near vision was much better than for a monofocal IOL and an EDOF lens made from a similar material, objective optical quality was reported to be slightly lower. 14,15 The Tecnis Symfony IOL is an EDOF lens that has been demonstrated to provide good intermediate and distance vision, with reported visual disturbances only slightly more severe than those experienced with a comparable monofocal IOL. 16 Halos were the most common visual disturbance associated with the lens.…”