Comparative analysis between two blood gas analyzers: ABL90 FLEX® VS. GEM4000®

Jeidane, I.; Mecández, D. López; Gonzalez, Eric; Llamas, A. Castrillo; Vázquez, P. Plaza; Cenzual, M.Á. Cuadrado

doi:10.1016/j.cca.2019.03.1382

Cited by 2 publications

(2 citation statements)

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“…Since 2013 the MECU in Odense has had an ABL90™ FLEX® (Radiometer, Brønshøj, Denmark) (ABL) installed in the car as a standard stationary point-of-care device. The performance of this smaller device equals larger stationary analyzers, for example, the ABL835™ FLEX® (Radiometer, Denmark) and the GEM 4000® (Werfer, Austria) [ 20 , 21 ]. The ABL in the MECU has been slightly modified from its original design to withstand the gravitational forces that rapid driving and fast alterations in speed in the MECU entail.…”

Section: Methodsmentioning

confidence: 99%

Prehospital blood gas analyses in acute patients treated by a ground-based physician-manned emergency unit: a cohort study

Walther,

Lassen,

Mogensen

et al. 2023

Scand J Trauma Resusc Emerg Med

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Background The prehospital patients treated by ambulances and mobile emergency care units (MECU) are potentially critically ill or injured. Knowing the risks of serious outcomes in these patients is important for guiding their treatment. Some settings allow for prehospital arterial blood gas analyses. This study aimed to assess the outcomes of prehospital patients in relation to their prehospitally measured lactate, pH, and CO2 levels. The primary outcome was 7-day mortality. Methods This register-based cohort study included patients with one or more prehospital blood gas analyses during their prehospital treatment by a physician-manned MECU, from January 2015 to December 2018. The blood samples were analyzed on an ABL90 Flex analyzer. Absolute values with percentages and odds ratios (OR) with 95% confidence intervals (CI) were calculated for the primary and secondary outcomes within prespecified subgroups. Results The study included 745 patients, with an overall 7-day mortality rate of 20.0%. Lactate level The 7-day mortality rates were 11.5% in patients with normal lactate levels (< 2.0 mmol/L), 14.4% with intermediate lactate levels (2.0–3.9 mmol/L), and 33.0% with high lactate levels (≥ 4.0 mmol/L). This corresponded to an OR of 1.30 (95% CI: 0.75–2.24) in the intermediate lactate group (2.0–3.9 mmol/L) and an OR of 3.77 (95% CI: 2.44–5.85) in the high lactate group (≥ 4.0 mmol/L), compared to the reference group with normal lactate. pH level The ORs of 7-day mortality rates were 4.82 (95% CI: 3.00–7.75) in patients with blood pH of < 7.35 and 1.33 (95% CI: 0.65–2.72) in patients with blood pH > 7.45, compared to the reference group with normal pH (7.35–7.45). CO2 level The ORs of 7-day mortality rates were 2.54 (95% CI: 1.45–4.46) in patients with blood CO2 of < 4.3 kPa and 2.62 (95% CI: 1.70–4.03) in patients with blood CO2 > 6.0 kPa, compared to the reference group with normal CO2 (4.3–6.0 kPa). Conclusions This study found a strong correlation between increasing 7-day mortality rates and high blood lactate levels, low levels of pH, and abnormal CO2 blood levels, in prehospital patients undergoing prehospital blood analysis.

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Section: Methodsmentioning

confidence: 99%

Prehospital blood gas analyses in acute patients treated by a ground-based physician-manned emergency unit: a cohort study

Walther,

Lassen,

Mogensen

et al. 2023

Scand J Trauma Resusc Emerg Med

View full text Add to dashboard Cite

show abstract

“…The performance of this smaller device equals larger stationary analyzers, for example, the ABL835™ FLEX® (Radiometer, Denmark) and the GEM 4000® (Werfer, Austria). (19,20) The ABL in the MECU has been slightly modi ed from its original design to withstand the gravitational forces that rapid driving and fast alterations in speed in the MECU entail. The ABL is placed in a specially designed cushioned cradle in the passenger seat of the car.…”

Section: Study Materialmentioning

confidence: 99%

Prehospital Blood Gas Analyses in Acute Patients treated by a Ground-based Physician-manned Emergency Unit: A Cohort Study

Walther,

Lassen,

Mogensen

et al. 2023

Preprint

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Background: The prehospital patients treated by ambulances and mobile emergency care units (MECU) are potentially critically ill or injured. Knowing the risks of serious outcomes in these patients is important for guiding their treatment. Some settings allow for prehospital arterial blood gas analyses. This study aimed to assess the outcomes of prehospital patients in relation to their prehospitally measured lactate, pH, and CO2 levels. The primary outcome was 7-day mortality. Methods: This register-based cohort study included patients with one or more prehospital blood gas analyses during their prehospital treatment by a physician-manned MECU, from January 2015 to December 2018. The blood samples were analyzed on an ABL90 Flex analyzer. Absolute values with percentages and odds ratios (OR) with 95% confidence intervals (CI) were calculated for the primary and secondary outcomes within prespecified subgroups. Results: The study included 745 patients, with an overall 7-day mortality rate of 20.0%. Lactate level: The 7-day mortality rates were 11.5% in patients with normal lactate levels (<2.0 mmol/L), 14.4% with intermediate lactate levels (2.0-3.9 mmol/L), and 33.0% with high lactate levels (≥4.0 mmol/L). This corresponded to an OR of 1.30 (95% CI: 0.75-2.24) in the intermediate lactate group (2.0-3.9 mmol/L) and an OR of 3.77 (95% CI: 2.44-5.85) in the high lactate group (≥4.0 mmol/L), compared to the reference group with normal lactate. pH level: The ORs of 7-day mortality rates were 4.82 (95% CI: 3.00-7.75) in patients with blood pH of <7.35 and 1.33 (95% CI: 0.65-2.72) in patients with blood pH >7.45, compared to the reference group with normal pH (7.35-7.45). CO2 level: The ORs of 7-day mortality rates were 2.54 (95% CI: 1.45-4.46) in patients with blood CO2 of <4.3 kPa and 2.62 (95% CI: 1.70-4.03) in patients with blood CO2 >6.0 kPa, compared to the reference group with normal CO2 (4.3-6.0 kPa). Conclusions: This study found a strong correlation between increasing 7-day mortality rates and high blood lactate levels, low levels of pH, and abnormal CO2 blood levels, in prehospital patients undergoing prehospital blood analysis. Prehospital risk stratification may be aided by Point-of-care blood gas analysis at the prehospital scene.

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Comparative analysis between two blood gas analyzers: ABL90 FLEX® VS. GEM4000®

Cited by 2 publications

References 0 publications

Prehospital blood gas analyses in acute patients treated by a ground-based physician-manned emergency unit: a cohort study

Prehospital blood gas analyses in acute patients treated by a ground-based physician-manned emergency unit: a cohort study

Prehospital Blood Gas Analyses in Acute Patients treated by a Ground-based Physician-manned Emergency Unit: A Cohort Study

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