2007
DOI: 10.1590/s1806-37132007000100010
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Comparação entre a azitromicina e a amoxicilina no tratamento da exacerbação infecciosa da doença pulmonar obstrutiva crônica

Abstract: Objective: To compare the efficacy, safety, and tolerability of azithromycin and amoxicillin in the treatment of patients with infectious exacerbation of chronic obstructive pulmonary disease. Methods: This study was conducted at six medical centers across Brazil and included 109 patients from 33 to 82 years of age. Of those, 102 were randomized to receive either azithromycin (500 mg/day for three days, n = 49) or amoxicillin (500 mg every eight hours for ten days, n = 53). The patients were evaluated at the s… Show more

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Cited by 8 publications
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“…The shortest follow-up time was 10 days and the longest was 1 year 3 months. All the included studies were RCTs and 4 studies were open-label [ 23 , 30 , 31 , 36 ]. Overall, the quality of the studies was ideal (Fig.…”
Section: Resultsmentioning
confidence: 99%
“…The shortest follow-up time was 10 days and the longest was 1 year 3 months. All the included studies were RCTs and 4 studies were open-label [ 23 , 30 , 31 , 36 ]. Overall, the quality of the studies was ideal (Fig.…”
Section: Resultsmentioning
confidence: 99%