Comparação De Duas Técnicas Inalatórias Para Administrar Broncodilatador Em Crianças E Adolescentes Com Crise Aguda De Asma: Metanálise

Abstract

Objective: To compare the efficacy of pediatric asthma treatment by nebulizer and metered-dose inhaler with the use of a spacer (MDI-spacer) in rescue techniques for asthmatic patients assisted at pediatric emergency units.Data sources: A systematic review was conducted to identify the most relevant randomized controlled trials comparing the administration of a bronchodilator (β-2 agonist) by two inhalation techniques (nebulization and MDI-spacer) to treat asthma in children at pediatric emergency units. The following databases were searched: PubMed, Scientific Electronic Library Online (SciELO), and ScienceDirect. Two researchers independently applied the eligibility criteria, and only randomized controlled trials that compared both inhalation techniques (nebulization and MDI-spacer) for asthma treatment at pediatric emergency units were included.Data synthesis: 212 articles were pre-selected, of which only nine met the eligibility criteria and were included in meta-analysis. Results show no differences between inhalation techniques for any of the four outcomes analyzed: heart rate (difference - Df: 1.99 [95% confidence interval - 95%CI -2.01-6.00]); respiratory rate (Df: 0.11 [95%CI -1.35-1.56]); O2 saturation (Df: -0.01 [95%CI -0.50-0.48]); and asthma score (Df: 0.06 [95%CI -0,26-0.38]). Conclusions: The findings demonstrate no differences in cardiorespiratory frequency, O2 saturation, and asthma scores upon administration of β-2 agonist by both inhalation techniques (nebulization and MDI-spacer) to asthmatic patients assisted at pediatric emergency units.

Approach to childhood asthma in the era of COVID-19

“…For the past few years, many institutions around the world have adopted using MDIs with VHCs instead of nebulization [ 32 ]. This is based on the fact that the two inhalation techniques yield similar clinical scores and outcomes [ 33 ].…”

Quality of Life of Children and Adolescents Who Live With Asthma

“…The assessment of quality of life has assumed an important role, with regard to the perception of both individual and collective implications of patients with asthma and other chronic diseases (RONCADA et al, 2013). One way to assess the implications caused by the disease is through the quality of life (QoL), because over the years, with age and experiences, the perception that the individual has about the disease undergoes several changes.…”