Abstract:SUMMARYWhether and to what extent sodium chloride infusions elevate blood pressure acutely were examined in conscious, normotensive, and spontaneously hypertensive (SHR) anephric rats. All animals were bilaterally nephrectomized 18 hours before study.Normotensive Wistar rats, allowed no food or water post nephrectomy (Groups I-IV), received either no infusion (Group I, control) or intravenous infusion of isotonic solutions of either NaCI, mannitol, or dextrose at a rate of 0.018 ml/min for 2 hours. Mean arteri… Show more
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