Comparability of Digital Photography with the ETDRS Film Protocol for Evaluation of Diabetic Retinopathy Severity

Ultra-wide Field Retinal Imaging in Detection, Classification, and Management of Diabetic Retinopathy

“…[12][13][14] These validation studies provide the support for the use of digital images instead of 35mm slides, which now are difficult to get processed and can be onerous in terms of handling and storage. Because of their excellent agreement 222 A.…”

Practice Guidelines for Ocular Telehealth-Diabetic Retinopathy, Third Edition

“…Although no standard criteria have been widely accepted as performance measurements of digital imagery used for DR evaluation, current clinical trials sponsored by the National Eye Institute have transitioned to digital images for DR assessment. 7,8 Telehealth programs for DR should demonstrate an ability to compare favorably with ETDRS film or digital photography as reflected in kappa values for agreement of diagnosis, falsepositive and false-negative readings, positive predictive value, negative predictive value, sensitivity and specificity of diagnosing levels of DR and diabetic macular edema (DME). [9][10][11][12] Because programs have reported referral-warranted ocular disease in many patients with ungradable images, inability to obtain or grade images should be considered a positive finding and patients with unobtainable or ungradable images should be promptly reimaged or referred for a more advanced evaluation.…”

Chemoselective reduction of nitro and nitrile compounds using an Fe3O4-MWCNTs@PEI-Ag nanocomposite as a reusable catalyst

“…On the other hand, reduction of nitrile compounds by NaBH 4 or LiAlH 4 usually leads to the production of amides instead of amines and therefore they cannot provide chemoselectivity. 29 Hence, study on effective and green methodologies for chemoselective transformation of nitrile and nitro compounds to amines is still of a great interest. In recent years, the abundance of published reports on the application of multi-walled carbon nanotubes (MWCNTs) is testimony to the considerable attention to functionalization of these carbon scaffolds for various applications such as oxidative dehydrogenation, [30][31][32] sensors for determination of DNA, 33 and MRI contrast agents.…”