Compact Multichannel Device for Differential Impedance Spectroscopy of Microfluidic Sensors

Ojarand, Jaan; Ehrminger, Robin; Min, Mart; Koel, Ants

doi:10.1109/bec.2018.8600955

Cited by 1 publication

(1 citation statement)

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“…The current article is an extended revision of the recent conference paper [1], in which impedimetric microfluidic devices target facilitation of dielectric and conductivity measurements of small fluidic volumes. The measuring fluid may be an electrolyte cell suspension or microparticles, a biochemical solution of metabolites, proteins, and nucleic acids [2,3].…”

Section: Introductionmentioning

confidence: 99%

Multichannel Electrical Impedance Spectroscopy Analyzer with Microfluidic Sensors

Ojarand

Min

Koel

2019

Sensors

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Impedance spectroscopy is a common approach in assessing passive electrical properties of biological matter. However, several problems appear in microfluidic devices in connection with the requirement for high sensitivity of signal acquisition from small volume sensors. The developed compact and inexpensive analyzer provides impedance spectroscopy measurement from three sensors, both connected in direct and differential modes. Measurement deficiencies are reduced with a novel design of sensors, measurement method, optimized electronics, signal processing, and mechanical design of the analyzer. Proposed solutions are targeted to the creation of reliable point-of-care (POC) diagnostic and monitoring appliances, including lab-on-a-chip type devices in the next steps of development. The test results show the good working ability of the developed analyzer; however, also limitations and problems that require attention and further improvement are appointed.

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Section: Introductionmentioning

confidence: 99%