Compact coiled flow inverter for process intensification

Soni, Surbhi; Sharma, Loveleen; Meena, Priya; Roy, Shantanu; Nigam, K.D.P.

doi:10.1016/j.ces.2018.09.008

Cited by 31 publications

(13 citation statements)

References 35 publications

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“…One way to realize this is by changing the flow geometry which can enhance the reaction rate using swirl flow [24], cyclonic flow [25], or by using a curved design reactor. Curved design (including coiled tubes) has been widely adopted to achieve higher heat and mass transfer as well as better performance mixing and reaction [26]. This curved design has also been implemented as a micro-combustor for thermo-photovoltaic application [27].…”

Section: Introductionmentioning

confidence: 99%

Numerical Evaluation of Potential Catalyst Savings for Ventilation Air Methane Catalytic Combustion in Helical Coil Reactors with Selective Wall Coating

et al. 2019

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During active mining operation of a gassy underground mine, large amounts of methane will be released from the mine ventilation shaft. To eliminate the harmful effects of this ventilation air methane and minimize the wastage of this potential energy resource, considerable effort has been devoted to converting this alternative fuel using catalytic combustion. This study numerically investigated the reaction performance of ventilation air methane (VAM) in helical coil tubes of various configurations utilizing a computational fluid dynamics (CFDs) approach. Several key factors affecting the catalytic combustion performance such as curvature, inlet Reynolds number, and cross-section aspect ratio were evaluated. Recalling the high cost of the catalyst used in this reaction—platinum—optimization of catalyst usage by implementing selective catalyst coating was conducted and investigated. For evaluation purposes, the reaction performance of the helical coil tube was compared to its straight counterpart. The results gave a firm confirmation of the superior performance of the helical coil tube compared to the straight one. In addition, it was found that the selective inner wall coating in the circular cross-section at a higher Reynolds number gave rise to the highest figure of merit (FoM), defined as the net energy produced per mg of catalyst platinum.

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Section: Introductionmentioning

confidence: 99%

Numerical Evaluation of Potential Catalyst Savings for Ventilation Air Methane Catalytic Combustion in Helical Coil Reactors with Selective Wall Coating

et al. 2019

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“…These include the use as reactor (Mandal, Serra, Hoarau, & Nigam, ; Sharma, Agarwal, Pathak, Nigam, & Rathore, ; Slominski, Seider, Churchill, & Seader, ), heat exchanger (Kumar, Mridha, Gupta, & Nigam, ; Singh & Nigam, ) or crystallizer (Hohmann et al, ). Furthermore, the CFI was used for liquid–liquid extraction (Kurt, Vural Gürsel, Hessel, Nigam, & Kockmann, ), liquid–liquid mixing (Mandal, Aggarwal, & Nigam, ; Mridha & Nigam, ), single‐phase mixing (Sharma, Nigam, & Roy, ; Soni, Sharma, Meena, Roy, & Nigam, ), or gas–liquid mixing (Kurt, Warnebold, Nigam, & Kockmann, ).…”

Section: Introductionmentioning

confidence: 99%

Simulation of continuous low pH viral inactivation inside a coiled flow inverter

David

Bayer

Lobedann

et al. 2020

Biotech & Bioengineering

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Continuous production of monoclonal antibodies is gaining more and more importance. To ensure continuous flow through the entire process as well as viral safety, continuous viral clearance needs to be investigated as well. This study focuses on low pH viral inactivation inside a coiled flow inverter (CFI). Computational fluid dynamics (CFD) simulation is used to gain further insight into the inactivation process inside the apparatus. The influence of viruses in comparison to different tracer elements on the residence time distribution (RTD) behavior is investigated. Finally, the viral inactivation kinetics are implemented into the CFD simulation and real process conditions are simulated. These are compared to experimental results. To the authors' knowledge, this study represents the first successful simulation of continuous viral inactivation inside a CFI. It allows the detailed analysis of processes inside the apparatus and the prediction of experimental virus study results and will therefore contribute to the effective planning of future validation studies.

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“…Mixers with a screw working element [4,5,6] are more energyconsuming, but can produce better mixtures. High-speed and low-speed circulation mixers [7,8] are applicable for liquids, but problematic for bulk mixtures. Paddle-type mixers require more energy, but they evenly distribute the components throughout the volume of the mixture [9,10].…”

Section: Introductionmentioning

confidence: 99%

Modelling the effect of continuous mixer operating parameters on mixture quality

et al. 2020

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The aim of the research was to obtain a regression model of the influence of some structural and kinematic parameters of a continuous mixer working element on the quality of the prepared mixture. The research methodology included the analysis of the design of the mixing unit and the identification of factors that could significantly affect the quality of the mixture. Later, on the basis of the experimental studies, the quality of the mixture at given values of factors was determined and a regression model was established. The developed functional diagram of a continuous mixing unit made it possible to establish factors that most intensively affected the quality of the prepared mixture. The obtained adequate regression model of the coefficient of variation of the content of the control component in the samples of the mixture indicated an improvement in the quality of the mixture with an increase in the frequency of rotation of the mixers and the number of the arms levels. In terms of quality indicators, a rotation frequency of about 1500 rpm was most preferable with a number of mixer levels of at least 5.

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Compact coiled flow inverter for process intensification

Cited by 31 publications

References 35 publications

Numerical Evaluation of Potential Catalyst Savings for Ventilation Air Methane Catalytic Combustion in Helical Coil Reactors with Selective Wall Coating

Numerical Evaluation of Potential Catalyst Savings for Ventilation Air Methane Catalytic Combustion in Helical Coil Reactors with Selective Wall Coating

Simulation of continuous low pH viral inactivation inside a coiled flow inverter

Modelling the effect of continuous mixer operating parameters on mixture quality

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