1992
DOI: 10.1037/0022-006x.60.6.845
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Comorbidity of schizophrenia and substance abuse: Implications for treatment.

Abstract: The problem of substance abuse disorders in schizophrenia patients is reviewed, including the prevalence of co-morbid disorders, assessment, hypothesized mechanisms underlying abuse, and the clinical effects of abuse on the course of illness and cognitive functioning. The principles of treatment for dual-diagnosis schizophrenia patients are outlined, and the limitations of existing interventions are noted. Gaps in current knowledge about the impact of substance abuse on schizophrenia and its treatment are iden… Show more

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Cited by 243 publications
(194 citation statements)
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“…These data further call into question the current bifurcation of the behavioral health field into two distinct and heavily bounded territories. 17,18 While work such as the review by Drake and colleagues cited above has sought to overcome this split in the field by repeatedly highlighting the importance of providing integrated care for persons with co-occurring disorders, systemic efforts continue to lag behind and to encounter numerous obstacles. These obstacles range from historical, political, ideological, professional, and fiscal/structural issues at one end of the spectrum (e.g., separate funding streams, independent state agencies) to practical and logistical issues at the other end.…”
Section: Introductionmentioning
confidence: 96%
“…These data further call into question the current bifurcation of the behavioral health field into two distinct and heavily bounded territories. 17,18 While work such as the review by Drake and colleagues cited above has sought to overcome this split in the field by repeatedly highlighting the importance of providing integrated care for persons with co-occurring disorders, systemic efforts continue to lag behind and to encounter numerous obstacles. These obstacles range from historical, political, ideological, professional, and fiscal/structural issues at one end of the spectrum (e.g., separate funding streams, independent state agencies) to practical and logistical issues at the other end.…”
Section: Introductionmentioning
confidence: 96%
“…Cuffel [6] observed as early as 1992 that more recent studies report a higher prevalence of substance abuse in schizophrenics than do older studies; the term "dual-diagnosis" patients was introduced to describe this type of patient. High prevalence estimates for alcoholism in schizophrenia have been reported in very different samples and regions, such as the United Kingdom, the United States (for review see [28,42,44], Germany [46], and Australia [13]. The estimated prevalence of alcoholism is clearly higher than that of other drugs of abuse, but figures for cannabis and cocaine are also comparatively high [31].…”
mentioning
confidence: 96%
“…There is now substantial evidence that substance use, especially alcoholism, is a significant problem in schizophrenia, with clinical samples reporting a prevalence of 30-50% [23,27,28,29,31,42]. Cuffel [6] observed as early as 1992 that more recent studies report a higher prevalence of substance abuse in schizophrenics than do older studies; the term "dual-diagnosis" patients was introduced to describe this type of patient.…”
mentioning
confidence: 97%
“…(Dixon 1999;Mueser et al 1992) Similar effects have been noted for individuals with affective disorders (Allen and RJ 1986).…”
Section: Discussionmentioning
confidence: 50%