Comorbidity in patients with cancer: Prevalence and severity measured by cumulative illness rating scale

Wedding, Ulrich; Roehrig, Bernd; Klippstein, Almuth; Steiner, Peggy med.; Schaeffer, Thomas; Pientka, Ludger; Höffken, K.

doi:10.1016/j.critrevonc.2006.11.001

Cited by 84 publications

(38 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An advantage of CIRS-G is the registration of morbidities in defined organ systems [11,12,16]. Depending on the inclusion criteria, this score among geriatric patients lies between 19.7 [23], 5.5 [29] and 2.4 [30], whereby the CIRS-G in studies such as ours on elective surgery in very elderly patients is seen to be in the lower range [30]. The comparatively low CIRS-G score of 4.07 in our study shows that the elderly patients who underwent pelvic floor surgery in our department had relatively good general conditions and following their entitlement to an appropriate quality of life chose to undergo elective urogynaecological surgery.…”

Section: Co-morbidity Analysismentioning

confidence: 99%

Gynaecological Prolapse Surgery in Very Old Female Patients

Mothes

Kwetkat

Radosa

et al. 2016

Geburtshilfe Frauenheilkd

View full text Add to dashboard Cite

Hintergrund: Ziel ist der Vergleich von hochaltrigen Patientinnen mit einer jüngeren Kontrollgruppe nach Deszensuschirurgie hinsichtlich Komorbidität und Komplikationen. Methode: Im Fallkontrolldesign erfolgte die Analyse konsekutiver Daten nach Deszensuschirurgie ab 80. Lebensjahr und einer Kontrollgruppe mittels Clavien-Dindo-(CD-)Klassifikation chirurgischer Komplikationen, Charlson Comorbidity Index und Cumulative Illness Rating Scale Geriatrics (CIRS-G). Statistik: Studentʼs t-, Fisherʼs Exactund Mann-Whitney U-Tests. Ergebnisse: Es wurden n = 57 vs. n = 60 Operationen erfasst. Bei Hochaltrigen lag häufiger ein Grad-IV-Prolaps vor (p < 0,001), es erfolgte häufiger eine apikale Fixation (p < 0,001), die OP-Zeiten unterschieden sich nicht. Bei Hochaltrigen fanden sich 21% CD-II + III-Komplikationen, in der Kontrollgruppe 6,6 % (p = 0,031). In beiden Gruppen traten keine CD-IV-und-V-Komplikationen auf, die Verweildauer lag bei 5 (± 1) vs. 4,1 (± 0,8; p < 0,001) Tagen, eine stationäre Weiterbetreuung erfolgte häufiger bei hochaltrigen Patientinnen (p < 0,001). Die Komorbidität Hochaltriger unterschied sich von der Kontrollgruppe in der Anzahl (median 2,0 vs. 1,5; p < 0,001), im CIRS-G (4,1 ± 2,2 vs. 2,4 ± 1,7; p < 0,001) und im Charlson-Index (1,6 ± 1,6 vs. 0,5 ± 0,7; p < 0,001). Schlussfolgerungen: Ein Deszensus kann bei hochaltrigen Patientinnen sicher chirurgisch versorgt werden. Komplikationen erreichten in keinem Fall Intensivtherapiepflichtigkeit oder Lebensbedrohlichkeit, führten aber zu einer verlängerten Verweildauer und häufiger zu geriatrischer oder internistischer stationärer Weiterbehandlung.

show abstract

Section: Co-morbidity Analysismentioning

confidence: 99%

Gynaecological Prolapse Surgery in Very Old Female Patients

Mothes

Kwetkat

Radosa

et al. 2016

Geburtshilfe Frauenheilkd

View full text Add to dashboard Cite

show abstract

“…This is due to 2 reasons: First, to date, a superiority of R-CHOP-14 over R-CHOP- 21 has not yet been shown in randomized trials and, second, many oncologists without experience with R-CHOP-14 are concerned because they assume a higher toxicity of the 2-week regimen.…”

Section: R-chop-14 Versus R-chop-21mentioning

confidence: 99%

“…Comorbidities and their functional consequences can be measured by the Cumulative Illness Rating Scale. 21 However, conduction of a complete geriatric assessment (CGA) is time-consuming and often impractical in a modern oncology practice, given logistic and resource constraints. Screening tools (eg, Vulnerable Elders Survey; VES-13 22 ) to identify those at-risk patients in need of a more formal CGA require prospective validation in oncology.…”

Section: Comorbidities and Organ Dysfunctionsmentioning

confidence: 99%

How I treat elderly patients with diffuse large B-cell lymphoma

Pfreundschuh

2010

Blood

130

View full text Add to dashboard Cite

show abstract

“…It can be seen from the American SEER program that in patients presenting colorectal cancer after 80 years of age, multimorbidity (congestive heart failure, chronic obstructive pulmonary disease, diabetes mellitus) is common and exerts a substantial effect on survival with close to 21% of deaths attributable to these comorbidities [13]. It could be more relevant to take into consideration the performance status or (preferably) the CIRS-G (Cumulative Illness Rating Scale in Geriatrics Score) at the time of diagnosis [26].…”

Section: Discussionmentioning

confidence: 99%