Comorbidity and temporal ordering of alcohol use disorders and other psychiatric disorders: results from a Danish register-based study

Flensborg‐Madsen, Trine; Mortensen, Erik Lykke; Knop, Joachim; Becker, Ulrik; Sher, Leo; Grønbæk, Morten

doi:10.1016/j.comppsych.2008.09.003

Cited by 86 publications

(95 citation statements)

References 51 publications

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“…In contrast to a large body of literature from other countries indicating moderate to strong positive correlations between AUD and non-AUD mental disorders (Andrews et al 2002;Kessler et al 2005;Hasin et al 2007;Flensborg-Madsen et al 2009;Markon, 2010;Chou et al 2012), this large, representative study from China found that men with AUD were significantly less likely to have other mental disorders than men who do not have AUD. The demographic correlates of AUD were also different from those reported elsewhere: compared with men without AUD, men with AUD in the absence of other mental disorders were more likely to be middle-aged, to be currently married, and to have higher family incomes.…”

Section: Main Findingscontrasting

confidence: 99%

Co-occurrence of DSM-IV mental disorders and alcohol use disorder among adult Chinese males

Cheng

Phillips

et al. 2017

Psychol. Med.

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Background. Studies from high-income countries report moderate-to-strong positive associations between alcohol use disorder (AUD) and other mental disorders, but there is little evidence about the comorbidity of AUD from low-andmiddle-income countries.Methods. A sample of 74 752 adults from five provinces that account for >12% of China's adult population was screened using the General Health Questionnaire, and the Structured Clinical Interview for DSM-IV was administered by psychiatrists to a subsample of 9619 males. The associations between AUD and other mental disorders at each site and the characteristics of men with AUD with and without comorbid mental disorders were estimated using logistic regression and summarized across sites using meta-analysis. Generalized estimation equations estimated the associations between the clinical features of alcohol dependence and comorbidity.Results. Robust inverse associations were found between current AUD and any mood disorder (adjusted OR = 0.6, 95% CI = 0.4-0.8) and any anxiety disorder (OR = 0.5, 95% CI = 0.3-1.0). Compared with men without AUD, men with AUD without comorbid disorders were more likely to be middle-aged, to be currently married, and to have higher family incomes. Men with comorbid AUD and other disorders were more likely to have the clinical features of alcohol dependence than men with AUD without comorbid disorders. Conclusions.Inverse associations between AUD and other mental disorders and the higher social status of men with AUD than men without AUD found in this large, representative sample of community-dwelling Chinese males highlight the importance of considering the local substance-use culture when designing clinical or preventive interventions for addictive conditions.

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Section: Main Findingscontrasting

confidence: 99%

Co-occurrence of DSM-IV mental disorders and alcohol use disorder among adult Chinese males

Cheng

Phillips

et al. 2017

Psychol. Med.

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“…These apparently paradoxical results -better compliance from the more severe subgroup of patients -are in consonance to previous affirmations that ADS treatment programs that focus on comorbidity will probably lead to better outcomes 6,20,24,30 . Alcoholic patients with worse clinical and psychiatric conditions do need pharmacological treatment whereas lower severity patients -possibly without relevant comorbidity -may be assisted by less sophisticated and even by self-help programs 32,33 .…”

Section: Discussionmentioning

confidence: 47%

“…The results here presented suggest that Cluster 1 patients may, in fact, be considered similar to Type A alcoholic patients (lower severity) and those included in Cluster 2 to Babor's Type B patients (higher overall severity) 4,16 . Although a correlation between heavy drinking and the development of psychiatric disorders other than alcoholism has not yet been demonstrated 24 , it is considered that a period of heavy drinking is essential to the development of an ADS 25 . Severe alcoholic patients often present more depressive and anxiety symptoms and tend to be more impulsive 26 and their psychopathological symptoms might be either relieved or aggravated by alcohol use 27,28 .…”

Section: Discussionmentioning

confidence: 99%

A possible contribution to improving the therapeutic potentials of Babor's Typology of Alcohol Dependent Patients

Ribeiro

Ferreira

2015

J. bras. psiquiatr.

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Objective: The objective of this study was to replicate Babor's Typology and to explore clinical features related to personality traits that may underlie this classification, in order to improve its therapeutic possibilities. Methods: Observational prospective study on a group of 273 male alcoholics. After a replication of Babor's variables, Cluster Analysis, Chi-Square -applied on clinical variables related to a Lappda Tipology -and Kappa tests were performed. Results: The study identified two distinct clusters that held similar features to those described for the Type A/Type B classification. Besides presenting a lower socio-economic situation, Cluster 2 patients were associated with higher vulnerability and severe clinical features and also differed from Cluster 1 in their response to treatment. These replicated clusters retained connections and also differences in relation to the variables derived from the Lappda Typology. Conclusion: Considering that each of the two replicated clusters seem to be associated to different personality traits -according to their correlations to the affective, cognitive and behavioral dimensions brought forward by the Lappda Typology -it is acceptable that this study may contribute to the development of more comprehensive and effective therapeutic strategies specifically tailored to target more specific personality traits of these subgroups of alcoholic patients. REsuMOObjetivo: O objetivo deste estudo foi replicar a tipologia do Babor e explorar características clínicas relacionadas a traços de personalidade que podem estar subjacentes a essa classificação, a fim de melhorar suas possibilidades terapêuticas. Métodos: Estudo observacional prospectivo em um grupo de 273 alcoolistas masculinos. Depois de uma replicação das variáveis de Babor, foram realizados Análise de Cluster, testes de Qui-quadrado -aplicados em variáveis clínicas relacionadas com uma tipologia desenvolvida pelo Lappda -e testes Kappa. Resultados: O estudo identificou dois clusters distintos que mantiveram características semelhantes àquelas descritas na classificação Tipo A/Tipo B. Além de apresentar uma pior situação socioeconômica, os pacientes do Cluster 1 foram associados a maior vulnerabilidade e a características clínicas de maior gravidade; e também diferiram do Cluster 2 em sua res-

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“…Den er bland andet knyttet til, at man har fået mere viden om den samtidige forekomst af psykisk sygdom og stofmisbrug, dels fra udenlandske undersøgelser (f.eks. Blanchard 2000; Grant et al 2004) og dels efterhånden også fra danske projekter og undersøgelser (Frederiksen 2009;Flensborg-Madsen et al 2009;Brasch et al 2011;Toftdahl et al 2015). En anden årsag er, at man generelt er blevet mere opmaerksom på helbredsproblemer hos stofmisbrugere, både hvad angår det fysiske og psykiske helbred.…”

Section: De Professionelles Perspektiv: Stofmisbrugsbehandlingunclassified

Jagten på en ADHD-diagnose: Analyse af situationer og kontekster, hvor det bliver attraktivt at være psykisk syg

Berger¹,

Johansen²

2016

TFSS

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Comorbidity and temporal ordering of alcohol use disorders and other psychiatric disorders: results from a Danish register-based study

Cited by 86 publications

References 51 publications

Co-occurrence of DSM-IV mental disorders and alcohol use disorder among adult Chinese males

Co-occurrence of DSM-IV mental disorders and alcohol use disorder among adult Chinese males

A possible contribution to improving the therapeutic potentials of Babor's Typology of Alcohol Dependent Patients

Jagten på en ADHD-diagnose: Analyse af situationer og kontekster, hvor det bliver attraktivt at være psykisk syg

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