Comorbid Depression, Chronic Pain, and Disability in Primary Care

Abstract

Chronic pain is common among those with MDD. Comorbid MDD and disabling chronic pain are associated with greater clinical burden than MDD alone.

Cost-Effectiveness of Early Versus Delayed Functional Restoration for Chronic Disabling Occupational Musculoskeletal Disorders

“…Within this context, however, it should also be noted that the literature documents alcohol abuse being correlated with, and sometimes as a precursor to, opioid dependence disorder (Ives et al, 2006;Turk, Swanson, & Gatchel, 2008). A similar confounding relationship for alcohol abuse has also been noted among patients with Major Depressive Disorder (Arnow et al, 2006). Consistent with the findings on Major Depressive Disorder, a substantially greater amount of patients in the late rehabilitation groups were observed with moderate-severe levels depressive symptoms as measures by the Hamilton Rating Scale for Depression (HAM-D).…”

The Canadian STOP-PAIN project – Part 1: Who are the patients on the waitlists of multidisciplinary pain treatment facilities?

“…Anxiety and anger were also common in this population. Table 7 Factors associated with severe chronic pain -Logistic regression analyses were performed to identify variables that distinguished patients with severe pain (C 7/10) from those who had pain of lesser intensity (\ 7/10) Numerous epidemiological and clinical studies [25][26][27][28][29][30] have documented the high prevalence of psychological comorbidities in patients with chronic pain, especially in those who experience significant limitations in their activities of daily living due to pain. For example, an international WHO survey of nearly 26,000 patients attending primary care facilities showed that chronic pain sufferers exhibited a four-fold increase in the odds of having an anxiety or depressive disorder relative to patients without persistent pain.…”

Comorbidade de sintomas ansiosos e depressivos em pacientes com dor crônica e o impacto sobre a qualidade de vida

“…Thus, many questions related to clinical characteristics and the burden of psychiatric comorbidity in chronic pain individuals still remain in this country. The strength of the relationship between chronic pain and major depression is unclear 11,12 especially with regard to HRQoL and depressive/anxiety symptoms.…”